Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.58 |
| ▸ | S100A4 | P26447 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9491013 | 1.00 | GPR35 (0.58) | GPR35S100A4ALDH1A1TDP1TSHR | |
| SCHEMBL3818387 | 0.88 | ALDH1A1 (0.46) | GPR35S100A4ALDH1A1TDP1TSHR | |
| SCHEMBL4963591 | 0.85 | GPR35 (0.58) | GPR35S100A4ALDH1A1TDP1TSHR | |
| SCHEMBL31395812 | 0.85 | GPR35 (0.58) | GPR35S100A4ALDH1A1TDP1TSHR | |
| SCHEMBL5929430 | 0.83 | GPR35 (0.56) | GPR35S100A4ALDH1A1TDP1TSHR | |
| SCHEMBL4274301 | 0.83 | GPR35 (0.56) | GPR35S100A4ALDH1A1TDP1TSHR | |
| SCHEMBL5281894 | 0.83 | GPR35 (0.56) | GPR35S100A4ALDH1A1TDP1TSHR | |
| SCHEMBL70533 | 0.81 | GPR35 (0.75) | GPR35S100A4ALDH1A1TDP1TSHR | |
| SCHEMBL3933610 | 0.81 | GPR35 (0.58) | GPR35ALDH1A1TDP1TSHRCA12 | |
| SCHEMBL3781650 | 0.81 | TDP1 (0.45) | GPR35S100A4ALDH1A1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118440025-B | Zhu Gongjun acid derivative and preparation method and application thereof | 济南爱思医药科技有限公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-118440025-A | Zhu Gongjun acid derivative and preparation method and application thereof | 济南爱思医药科技有限公司 | 2024-08-06 | — | — | CN | disclosed |