Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.56 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | IP6K2 | Q9UHH9 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3100220 | 0.83 | NPC1 (0.55) | ESR1ESR2ERN1HPGDKDM4E | |
| SCHEMBL3102505 | 0.83 | KDM4E (0.50) | ESR1ESR2KDM4EALDH1A1MAOB | |
| SCHEMBL3104199 | 0.82 | DDAH1 (0.46) | ERN1PTGESCYP3A4HPGDKDM4E | |
| SCHEMBL3106747 | 0.81 | EGFR (0.57) | ERN1CYP3A4HPGDKDM4EALDH1A1 | |
| SCHEMBL3099337 | 0.79 | ERN1 (0.44) | ESR1ESR2ERN1CYP3A4HPGD | |
| SCHEMBL3904591 | 0.79 | CYP1A1 (0.44) | ESR1ESR2CYP3A4HPGDKDM4E | |
| SCHEMBL3094847 | 0.79 | ERN1 (0.48) | ERN1HPGDALDH1A1 | |
| SCHEMBL13964506 | 0.76 | P2RY14 (0.41) | ESR1ESR2HPGDKDM4EALDH1A1 | |
| SCHEMBL30482423 | 0.76 | ESR1 (0.56) | ESR1ESR2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL3108897 | 0.76 | PIK3CD (0.35) | ESR1ESR2ERN1CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2210876-B1 | HETEROCYCLIC COMPOUND AS GLUCAGON ANTAGONIST | TAKEDA PHARMACEUTICAL (JP) | 2015-05-20 | — | — | EP | disclosed |
| US-8309580-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-11-13 | — | — | US | disclosed |
| US-20100256156-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-10-07 | — | — | US | disclosed |
| EP-2210876-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2010-07-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256156-A1 | HETEROCYCLIC COMPOUND | GLP1R, GPR119, GCGR | ESR1 606/4885ESR2 649/4885ERN1 1620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.