Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.78 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | BLVRB | P30043 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3101571 | 1.00 | ALDH1A1 (0.78) | ALDH1A1TDP1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL133647 | 0.88 | TDP1 (1.00) | ALDH1A1TDP1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL29359461 | 0.88 | TDP1 (1.00) | ALDH1A1TDP1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL133646 | 0.88 | TDP1 (1.00) | ALDH1A1TDP1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7033980 | 0.87 | TDP1 (0.97) | ALDH1A1TDP1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7033973 | 0.87 | TDP1 (0.97) | ALDH1A1TDP1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7033984 | 0.87 | TDP1 (0.97) | ALDH1A1TDP1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL3385330 | 0.83 | MEN1 (0.70) | ALDH1A1TDP1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1624756 | 0.83 | MEN1 (0.70) | ALDH1A1TDP1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL26730466 | 0.83 | MEN1 (0.70) | ALDH1A1TDP1SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825040-B2 | APPARTUS FOR USE IN THE DETECTION OF ACIDS IN SAMPLE | MAINSTREAM ENGINEERING CORPORATION | 2004-11-30 | — | — | US | claimed |
| US-8476390-B2 | Light filters comprising P-nitrophenylazo salicylic acid derivatives thereof | ARES CAPITAL CORPORATION, AS COLLATERAL AGENT | 2013-07-02 | — | — | US | disclosed |
| US-20100256306-A1 | LIGHT FILTERS COMPRISING P-NITROPHENYLAZO SALICYLIC ACID DERIVATIVES THEREOF | ARES CAPITAL CORPORATION, AS COLLATERAL AGENT | 2010-10-07 | — | — | US | disclosed |
| EP-2150588-A2 | POLYMERIC DYES BASED ON POLYMERIZABLE VINYL-GROUP CONTAINIG P-NITROPHENYL-AZO SALICYLIC ACID DERIVATIVES | Benz Research and Development Corporation (US) | 2010-02-10 | — | — | EP | disclosed |
| WO-2008134555-A2 | POLYMERIC DYES BASED ON POLYMERIZABLE VINYL-GROUP CONTAINING P-NITROPHENYL-AZO SALICYLIC ACID DERIVATIVES | BENZ RESEARCH AND DEVELOPMENT CORPORATION (US) | 2008-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256306-A1 | LIGHT FILTERS COMPRISING P-NITROPHENYLAZO SALICYLIC ACID DERIVATIVES THEREOF | UACA, SUN2, VHL | ALDH1A1 356/4885TDP1 2883/4885SMN1; SMN2 4031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.