Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | GPR183 | P32249 | 3/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27228300 | 1.00 | CHRM2 (0.44) | CHRM2GPR183PRKAA2CYP2D6CYP3A4 | |
| SCHEMBL27228311 | 0.92 | CHRM2 (0.53) | CHRM2CYP2D6CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL31016691 | 0.90 | CYP2D6 (0.46) | CHRM2CYP2D6CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL27228352 | 0.90 | CYP2D6 (0.46) | CHRM2CYP2D6CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL31016698 | 0.88 | GPR6 (0.37) | CHRM2PRKAA2CYP2D6CYP3A4CYP2C19 | |
| SCHEMBL27228323 | 0.88 | CYP2C9 (0.53) | CYP2D6CYP3A4CYP2C19CYP2C9CYP1A2 | |
| SCHEMBL31016665 | 0.88 | CYP2C9 (0.53) | CYP2D6CYP3A4CYP2C19CYP2C9CYP1A2 | |
| SCHEMBL27228654 | 0.88 | GPR6 (0.37) | CHRM2PRKAA2CYP2D6CYP3A4CYP2C19 | |
| SCHEMBL27228577 | 0.88 | CYP2D6 (0.41) | CYP2D6CYP3A4CYP2C19CYP2C9CYP1A2 | |
| SCHEMBL31016707 | 0.87 | CHRM2 (0.37) | CHRM2CYP2D6CYP3A4CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240174671-A1 | New 2,3-Dihydro-1H-pyrrolo[3,2-b]pyridine Derivatives as Sigma Ligands | ACONDICIONAMIENTO TARRASENSE (ES) | 2024-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240174671-A1 | New 2,3-Dihydro-1H-pyrrolo[3,2-b]pyridine Derivatives as Sigma Ligands | SIGMAR1, OPRD1, TMEM97 | CHRM2 205/4885GPR183 329/4885PRKAA2 780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.