Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | PARP1 | P09874 | 3/20 | 0.52 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30184030 | 0.88 | PARP1 (0.56) | KDM4EALDH1A1HPGDHSD17B10PARP1 | |
| SCHEMBL3584981 | 0.88 | PARP1 (0.56) | KDM4EALDH1A1HPGDHSD17B10PARP1 | |
| SCHEMBL16938458 | 0.85 | HRH3 (0.59) | KDM4EALDH1A1HPGDHSD17B10PARP1 | |
| SCHEMBL554335 | 0.83 | ALDH1A1 (0.66) | KDM4EALDH1A1HPGDHSD17B10CREBBP | |
| SCHEMBL8918599 | 0.83 | GRIK1 (0.55) | KDM4EALDH1A1HPGDPARP1BRD4 | |
| SCHEMBL27535854 | 0.80 | CA12 (0.51) | KDM4EALDH1A1HPGDHSD17B10PARP1 | |
| SCHEMBL30694751 | 0.80 | XDH (0.61) | KDM4EALDH1A1HPGDHSD17B10CREBBP | |
| SCHEMBL5368743 | 0.79 | PARP1 (0.63) | KDM4EALDH1A1HPGDHSD17B10PARP1 | |
| SCHEMBL21326430 | 0.78 | CREBBP (0.50) | KDM4EALDH1A1HPGDHSD17B10PARP1 | |
| SCHEMBL30159581 | 0.78 | CREBBP (0.54) | KDM4EALDH1A1HPGDHSD17B10PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025098450-A1 | PRMT5 INHIBITOR AND PREPARATION METHOD THEREFOR | 北京泰德制药股份有限公司 | 2025-05-15 | — | — | WO | disclosed |
| CN-118359604-A | Protein arginine methyltransferase inhibitors | 华润医药研究院（深圳）有限公司 | 2024-07-19 | — | — | CN | disclosed |