Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | MGAM | O43451 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.47 |
| ▸ | KDM6B | O15054 | 1/20 | 0.45 |
| ▸ | KDM5C | P41229 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.45 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1665704 | 0.86 | HTT (0.56) | HTTALOX15KDM4EMAPK1L3MBTL1 | |
| SCHEMBL264131 | 0.85 | HTT (0.55) | HTTALOX15KDM4EMAPK1L3MBTL1 | |
| SCHEMBL69982 | 0.83 | MGAM (0.58) | ALOX15KDM4EL3MBTL1MGAMKDM6B | |
| SCHEMBL4302176 | 0.82 | MGAM (0.53) | ALOX15KDM4EMGAMALDH1A1PDE4B | |
| SCHEMBL15484343 | 0.82 | MGAM (0.56) | ALOX15KDM4EL3MBTL1MGAMKDM6B | |
| SCHEMBL4540728 | 0.81 | HTT (0.60) | HTTALOX15KDM4EMAPK1L3MBTL1 | |
| SCHEMBL30718816 | 0.81 | HTT (0.60) | HTTALOX15KDM4EL3MBTL1LCK | |
| SCHEMBL17203103 | 0.81 | HTT (0.60) | HTTALOX15KDM4EL3MBTL1LCK | |
| SCHEMBL23535667 | 0.79 | HTT (0.59) | HTTALOX15KDM4EL3MBTL1LCK | |
| SCHEMBL31413386 | 0.79 | HTT (0.59) | HTTALOX15KDM4EL3MBTL1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118359604-A | Protein arginine methyltransferase inhibitors | 华润医药研究院（深圳）有限公司 | 2024-07-19 | — | — | CN | disclosed |