SCHEMBL69982

SCHEMBL69982

O=C(O)c1ccc2nc(C(=O)O)ccc2c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 2/20 0.58
TDP1 Q9NUW8 4/20 0.50
P4HA1 P13674 1/20 0.47
MIF P14174 1/20 0.47
P4HTM Q9NXG6 1/20 0.47
ALOX15 P16050 2/20 0.47
TSHR P16473 2/20 0.47
HIF1A Q16665 1/20 0.47
KDM4E B2RXH2 7/20 0.46
NPC1 O15118 4/20 0.46
RAB9A P51151 4/20 0.46
ALDH1A1 P00352 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
GAA P10253 2/20 0.46
HPGD P15428 2/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
MAPT P10636 2/20 0.46
KDM6B O15054 1/20 0.46
TET3 O43151 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15484343 0.98 MGAM (0.56) MGAMTDP1P4HA1MIFP4HTM
SCHEMBL4302176 0.87 MGAM (0.53) MGAMTDP1P4HA1MIFP4HTM
SCHEMBL1668204 0.87 TDP1 (0.46) MGAMTDP1KDM4ENPC1RAB9A
SCHEMBL28278979 0.86 MGAM (0.60) MGAMTDP1P4HA1MIFP4HTM
SCHEMBL21290591 0.84 TDP1 (0.47) MGAMTDP1KDM4ENPC1RAB9A
SCHEMBL31017201 0.83 HTT (0.57) MGAMTDP1ALOX15KDM4ENPC1
SCHEMBL12405037 0.81 MGAM (0.63) MGAMTDP1P4HA1MIFP4HTM
SCHEMBL1309231 0.81 TDP1 (0.50) MGAMTDP1TSHRKDM4ENPC1
SCHEMBL2211860 0.81 MGAM (0.58) MGAMTDP1ALOX15TSHRKDM4E
SCHEMBL9220609 0.79 MGAM (0.61) MGAMTDP1P4HA1MIFP4HTM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 362 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1877466-B1 PROCESS FOR THE PRODUCTION OF POLYARENEAZOLE POLYMER DU PONT (US) 2014-02-26 EP claimed
CN-101213243-B Processes for preparing high inherent viscosity polyareneazoles using metal powders DU PONT 2011-06-22 CN claimed
CN-101805448-A Polybenzimidazole containing phenylsulfonyl side groups and preparation method thereof UNIV SHANGHAI JIAOTONG 2010-08-18 CN claimed
US-7776246-B2 Process for the production of polyarenazole yarn E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-08-17 US claimed
CN-101798387-A Polybenzothiazole sulfonate containing imidazole group and preparation method thereof UNIV SHANGHAI JIAOTONG 2010-08-11 CN claimed
CN-101717492-A Polybenzothiazole with sulfonate side group and preparation method thereof UNIV SHANGHAI JIAOTONG 2010-06-02 CN claimed
US-7683157-B2 Process for the production of polyarenazole polymer E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-03-23 US claimed
US-7671171-B2 Processes for preparing high inherent viscosity polyareneazoles using metal powders E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-03-02 US claimed
EP-1866467-B1 PROCESS FOR THE PRODUCTION OF POLYARENAZOLE YARN DU PONT (US) 2008-12-17 EP claimed
EP-1879942-B1 PROCESSES FOR PREPARING HIGH INHERENT VISCOSITY POLYARENEAZOLES USING METAL POWDERS MAGELLAN SYSTEMS INT LLC (US) 2008-12-03 EP claimed
CN-1250610-C Sulfonated benzoxaazole or sulfonated polybenzoxaazole and preparation thereof UNIV SHANGHAI JIAOTONG (CN) 2006-04-12 CN claimed
CN-1583832-A Polybenzoaazole with sulfonate as side group and its preparation UNIV SHANGHAI COMMUNICATION (CN) 2005-02-23 CN claimed
CN-1583831-A Benzimidazole with sulfonate as side group and benzoxaazole copolymer and its preparation UNIV SHANGHAI COMMUNICATION (CN) 2005-02-23 CN claimed
CN-1583833-A Sulfonated benzoxaazole or sulfonated polybenzoxaazole and preparation thereof UNIV SHANGHAI COMMUNICATION (CN) 2005-02-23 CN claimed
CN-1041208-C Rigid rod polymer based on pyridobisimidazole AKZO NOBEL NV (NL) 1998-12-16 CN claimed
EP-0696297-B1 RIGID ROD POLYMER BASED ON PYRIDOBISIMIDAZOLE AKZO NOBEL NV (NL) 1998-08-05 EP claimed
US-5674969-A Rigid rod polymer based on pyridobisimidazole AKZO NOBEL NV (NL) 1997-10-07 US claimed
CN-1121728-A Rigid rod polymer based on pyridobisimidazole AKZO NOBEL NV (NL) 1996-05-01 CN claimed
EP-0696297-A1 RIGID ROD POLYMER BASED ON PYRIDOBISIMIDAZOLE Akzo Nobel N.V. (NL) 1996-02-14 EP claimed
WO-1994025506-A1 RIGID ROD POLYMER BASED ON PYRIDOBISIMIDAZOLE AKZO NOBEL N.V. (NL) 1994-11-10 WO claimed