Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | HSD17B14 | Q9BPX1 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69982 | 0.87 | MGAM (0.58) | MGAMALDH1A1MAPTHPGDHSD17B14 | |
| SCHEMBL15484343 | 0.86 | MGAM (0.56) | MGAMALDH1A1MAPTHPGDHSD17B14 | |
| SCHEMBL18077323 | 0.85 | SCN7A (0.46) | CYP2A6ALDH1A1MAPTHPGDSCN7A | |
| SCHEMBL1644188 | 0.85 | CYP2A6 (0.46) | CYP2A6ALDH1A1MAPTHPGDSCN7A | |
| SCHEMBL31017201 | 0.82 | HTT (0.57) | MGAMALDH1A1MAPTGAATDP1 | |
| SCHEMBL21290591 | 0.80 | TDP1 (0.47) | MGAMALDH1A1MAPTHPGDHSD17B14 | |
| SCHEMBL31201668 | 0.79 | NPC1 (0.55) | CYP2A6ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL5095477 | 0.79 | NPC1 (0.55) | CYP2A6ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL6194060 | 0.79 | MEN1 (0.57) | MGAMCYP2A6ALDH1A1MAPTHPGD | |
| SCHEMBL1645117 | 0.77 | CYP2A6 (0.53) | CYP2A6ALDH1A1MAPTHPGDSCN7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2024272-A2 | AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | Renovis, Inc. (US) | 2009-02-18 | — | — | EP | claimed |
| WO-2007133637-A2 | AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | RENOVIS, INC. (US) | 2007-11-22 | — | — | WO | claimed |