Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2260258 | 0.92 | METAP1 (0.46) | METAP1ATRNAMPTSYKRAB9A | |
| SCHEMBL306384 | 0.79 | METAP1 (0.44) | METAP1ATRNAMPTRAB9AMAPT | |
| SCHEMBL31419186 | 0.79 | GAA (0.47) | METAP1ATRNAMPTSYKRAB9A | |
| SCHEMBL27611635 | 0.78 | METAP1 (0.46) | METAP1ATRNAMPTSYKRAB9A | |
| SCHEMBL29919656 | 0.76 | RAB9A (0.54) | METAP1RAB9AMAPTHTTNPC1 | |
| SCHEMBL68279 | 0.76 | RAB9A (0.54) | METAP1RAB9AMAPTHTTNPC1 | |
| SCHEMBL15266282 | 0.76 | METAP1 (0.56) | METAP1ATRNAMPTRAB9ACYP17A1 | |
| SCHEMBL27967000 | 0.76 | RAB9A (0.49) | METAP1ATRNAMPTRAB9AMAPT | |
| SCHEMBL15085418 | 0.76 | ATR (0.45) | METAP1ATRNAMPTSYKRAB9A | |
| SCHEMBL5466767 | 0.76 | LMNA (0.51) | METAP1ATRNAMPTTRPV1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118401516-A | TYK2 inhibitors, compositions and methods thereof | 凌科药业(杭州)有限公司 | 2024-07-26 | — | — | CN | disclosed |