Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.39 |
| ▸ | DRD3 | P35462 | 5/20 | 0.39 |
| ▸ | HTR1D | P28221 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 3/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTR5A | P47898 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4527853 | 1.00 | DRD2 (0.39) | DRD2DRD3HTR1DDRD4ELANE | |
| SCHEMBL30706241 | 0.94 | DRD2 (0.42) | DRD2DRD3HTR1DDRD4HTR5A | |
| SCHEMBL17048014 | 0.84 | DRD2 (0.39) | DRD2DRD3HTR1DDRD4KDM4E | |
| SCHEMBL28987318 | 0.84 | DRD2 (0.39) | DRD2DRD3HTR1DDRD4HTR5A | |
| SCHEMBL16797499 | 0.80 | ALDH1A1 (0.36) | HTR1DKDM4EMITFLMNAHPGD | |
| SCHEMBL29414143 | 0.80 | CA1 (0.50) | DRD2DRD3DRD4LMNAHTT | |
| SCHEMBL5599606 | 0.80 | CA1 (0.50) | DRD2DRD3DRD4LMNAHTT | |
| SCHEMBL16167379 | 0.79 | ELANE (0.38) | ELANEKDM4EMITFLMNAHPGD | |
| SCHEMBL16335527 | 0.79 | SMN1; SMN2 (0.37) | DRD2DRD3HTR1DDRD4ELANE | |
| SCHEMBL17284193 | 0.79 | DRD2 (0.40) | DRD2DRD3HTR1DDRD4NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118401516-A | TYK2 inhibitors, compositions and methods thereof | 凌科药业(杭州)有限公司 | 2024-07-26 | — | — | CN | disclosed |