Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRA | P18433 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | ITK | Q08881 | 2/20 | 0.31 |
| ▸ | INSR | P06213 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.30 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10279027 | 0.71 | — | — | |
| SCHEMBL20501825 | 0.66 | CSF1R (0.37) | SMN1; SMN2LMNACSF1RALDH1A1HSD17B10 | |
| SCHEMBL10170668 | 0.66 | PPARG (0.51) | PTPRASMN1; SMN2KDM6BLMNAALDH1A1 | |
| SCHEMBL10170669 | 0.66 | PPARG (0.51) | PTPRASMN1; SMN2KDM6BLMNAALDH1A1 | |
| SCHEMBL1826830 | 0.66 | PPARG (0.51) | PTPRASMN1; SMN2KDM6BLMNAALDH1A1 | |
| SCHEMBL5598116 | 0.66 | CSF1R (0.35) | SMN1; SMN2LMNACSF1RALDH1A1HSD17B10 | |
| SCHEMBL1206992 | 0.65 | — | — | |
| SCHEMBL282246 | 0.65 | — | — | |
| SCHEMBL9162758 | 0.64 | KDM6B (0.52) | PTPRAKDM6BHSD17B10OR51E2CYP2C9 | |
| SCHEMBL22188458 | 0.64 | LMNA (0.39) | SMN1; SMN2GRIA1GRIA3LMNACSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130323753-A1 | METHODS AND KITS FOR IDENTIFICATION OF ANTI-EXCITOTOXIC COMPOUNDS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2013-12-05 | — | — | US | disclosed |
| US-20100248986-A1 | METHODS AND KITS FOR IDENTIFICATION OF ANTI-EXCITOTOXIC COMPOUNDS | FIRESTEIN-MILLER BONNIE L | 2010-09-30 | — | — | US | disclosed |
| WO-2009033055-A1 | METHODS AND KITS FOR IDENTIFICATION OF ANTI-EXCITOTOXIC COMPOUNDS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2009-03-12 | — | — | WO | disclosed |
| US-6506928-B1 | Derivative in which fullerene is linked to at least one dendron having at least one protic group which imparts water solubility | SIEMENS AXIVA GMBH & CO. KG (DE) | 2003-01-14 | — | — | US | disclosed |