SCHEMBL31019249

SCHEMBL31019249

OB(O)Oc1ccc(F)c(O)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA3 P07451 1/20 0.46
CA6 P23280 1/20 0.46
CA5A P35218 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
CA5B Q9Y2D0 1/20 0.46
HSD17B1 P14061 4/20 0.40
HSD17B2 P37059 4/20 0.40
HSD17B14 Q9BPX1 2/20 0.38
CYP4F2 P78329 1/20 0.34
CYP4A11 Q02928 1/20 0.34
ADRB3 P13945 2/20 0.33
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33
GRM5 P41594 1/20 0.33
MEP1B Q16820 1/20 0.33
ADRB1 P08588 1/20 0.33
ADRA2A P08913 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29107394 0.83 ESR1 (0.40) CA3CA6CA5ACA9CA14
SCHEMBL3158582 0.83 MAOB (0.40) ESR1
SCHEMBL31366917 0.83 MAOB (0.40) ESR1
SCHEMBL25356026 0.80 APP (0.40) CA6TRIM24TYRTRIM33
SCHEMBL29184353 0.79 VCP (0.33)
SCHEMBL739930 0.78 HTR2A (0.38)
SCHEMBL30506427 0.78 SOS1 (0.44)
SCHEMBL740211 0.78 SOS1 (0.44)
SCHEMBL30631648 0.78 HTR2A (0.38)
SCHEMBL30078218 0.78 NR4A1 (0.35) ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115003671-B JNK inhibitors, pharmaceutical compositions and uses thereof 武汉朗来科技发展有限公司 2024-08-06 CN disclosed