Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.63 |
| ▸ | NPC1 | O15118 | 11/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21903679 | 0.85 | MEN1 (0.64) | RAB9ANPC1MEN1KMT2ATDP1 | |
| SCHEMBL20332881 | 0.85 | RAB9A (0.61) | RAB9ANPC1MEN1KMT2ATDP1 | |
| SCHEMBL29792071 | 0.85 | RAB9A (0.61) | RAB9ANPC1MEN1KMT2ATDP1 | |
| SCHEMBL21903692 | 0.83 | F2 (0.62) | RAB9ANPC1MEN1KMT2ATDP1 | |
| SCHEMBL14985581 | 0.82 | MEN1 (0.67) | RAB9ANPC1MEN1KMT2ATDP1 | |
| SCHEMBL3901088 | 0.80 | NPC1 (0.66) | RAB9ANPC1MEN1KMT2ATDP1 | |
| SCHEMBL31019644 | 0.80 | NPC1 (0.65) | RAB9ANPC1MEN1KMT2ATDP1 | |
| SCHEMBL11219536 | 0.80 | NPC1 (0.65) | RAB9ANPC1MEN1KMT2ATDP1 | |
| SCHEMBL27299415 | 0.80 | NPC1 (0.65) | RAB9ANPC1MEN1KMT2ATDP1 | |
| SCHEMBL20558362 | 0.79 | NPC1 (0.64) | RAB9ANPC1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011428-A1 | HETEROCYCLIC KINASE INHIBITORS | GB005, INC. (US) | 2021-01-21 | — | — | WO | disclosed |