Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22692164 | 1.00 | AKR1B1 (0.40) | AKR1B1 | |
| SCHEMBL30500659 | 0.80 | AKR1B1 (0.36) | AKR1B1 | |
| SCHEMBL8857027 | 0.80 | AKR1B1 (0.36) | AKR1B1 | |
| SCHEMBL31757604 | 0.80 | AKR1B1 (0.36) | AKR1B1 | |
| SCHEMBL309710 | 0.80 | AKR1B1 (0.36) | AKR1B1 | |
| SCHEMBL458801 | 0.80 | AKR1B1 (0.36) | AKR1B1 | |
| SCHEMBL458624 | 0.80 | AKR1B1 (0.36) | AKR1B1 | |
| SCHEMBL31757603 | 0.80 | AKR1B1 (0.36) | AKR1B1 | |
| SCHEMBL184297 | 0.78 | AKR1B1 (0.42) | AKR1B1 | |
| SCHEMBL27688172 | 0.78 | AKR1B1 (0.42) | AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115803333-A | Trinucleotide cap analogs, their preparation and use | 生命技术公司 | 2023-03-14 | — | — | CN | disclosed |
| US-20230050863-A1 | DICATIONIC FLUORESCENT DYES | ROCHE MOLECULAR SYSTEMS, INC. | 2023-02-16 | — | — | US | disclosed |
| US-11384376-B2 | Reagents and methods for post-synthetic modification of nucleic acids | ROCHE MOLECULAR SYSTEMS, INC. (US) | 2022-07-12 | — | — | US | disclosed |
| US-20220143198-A1 | COMPOSITIONS AND METHODS RELATED TO TETHERED KETHOXAL DERIVATIVES | THE UNIVERSITY OF CHICAGO (US) | 2022-05-12 | — | — | US | disclosed |
| US-20220002716-A1 | TRINUCLEOTIDE CAP ANALOGS, PREPARATION AND USES THEREOF | Life Technologies Corporation | 2022-01-06 | — | — | US | disclosed |
| US-20210214773-A1 | COMPOSITIONS AND METHODS RELATED TO KETHOXAL DERIVATIVES | THE UNIVERSITY OF CHICAGO (US) | 2021-07-15 | — | — | US | disclosed |
| WO-2021116037-A1 | DICATIONIC FLUORESCENT DYES | F. HOFFMANN-LA ROCHE AG (CH) | 2021-06-17 | — | — | WO | disclosed |
| EP-3802863-A1 | REAGENTS AND METHODS FOR POST-SYNTHETIC MODIFICATION OF NUCLEIC ACIDS | F. Hoffmann-La Roche AG (CH) | 2021-04-14 | — | — | EP | disclosed |
| EP-3790544-A1 | COMPOSITIONS AND METHODS RELATED TO KETHOXAL DERIVATIVES | The University of Chicago (US) | 2021-03-17 | — | — | EP | disclosed |
| CN-112154214-A | Reagents and methods for post-synthetic modification of nucleic acids | 豪夫迈·罗氏有限公司 | 2020-12-29 | — | — | CN | disclosed |
| WO-2002044416-A2 | SULFONATED DIARYLRHODAMINE DYES AS FLUORESCENT LABELS | APPLERA CORPORATION (US) | 2002-06-06 | — | — | WO | disclosed |
| WO-2002036832-A2 | ATROPISOMERS OF ASYMMETRIC XANTHENE FLUORESCENT DYES AND METHODS OF DNA SEQUENCING AND FRAGMENT ANALYSIS | APPLERA CORPORATION (US) | 2002-05-10 | — | — | WO | disclosed |
| WO-2002030944-A2 | FLUORESCENT NUCLEOBASE CONJUGATES HAVING ANIONIC LINKERS | APPLERA CORPORATION (US) | 2002-04-18 | — | — | WO | disclosed |
| EP-1196640-A2 | ELECTRON-DEFICIENT NITROGEN HETEROCYCLE-SUBSTITUTED FLUORESCEIN DYES | Applera Corporation (US) | 2002-04-17 | — | — | EP | disclosed |
| US-6358679-B1 | DETECTING TARGET NUCLEOTIDE SEQUENCES BY AMPLIFYING WITH FORWARD AND REVERSE PRIMER REAGANTS IN A SET OF ONE OR MORE VESSELS, AND AMPLIFYING A SINGLE STRANDED EXTERNAL CONTROL POLYNUCLEOTIDE WITH PRIMERS IN A SECOND SET OF VESSELS | PE CORPORATION (NY) | 2002-03-19 | — | — | US | disclosed |
| WO-2002016648-A2 | METHODS FOR EXTERNAL CONTROLS FOR NUCLEIC ACID AMPLIFICATION | PE CORPORATION (NY) (US) | 2002-02-28 | — | — | WO | disclosed |
| US-6348596-B1 | NUCLEIC ACID HYBRIDIZATION ASSAYS; DNA SEQUENCE DETERMINATION | PE CORPORATION (NY) | 2002-02-19 | — | — | US | disclosed |
| WO-2001083621-A2 | SULFONATED [8,9]BENZOPHENOXAZINE DYES AND THE USE OF THEIR LABELLED CONJUGATES | APPLERA CORPORATION (US) | 2001-11-08 | — | — | WO | disclosed |
| WO-2001057264-A2 | ELECTRON-DEFICIENT NITROGEN HETEROCYCLE-SUBSTITUTED FLUORESCEIN DYES | APPLERA CORPORATION (US) | 2001-08-09 | — | — | WO | disclosed |
| US-6221604-B1 | CONJUGATED TO SUBSTRATES SUCH AS NUCLEOSIDES OR NUCLEOTIDES AND USED AS DETECTION LABELS IN MOLECULAR BIOLOGY EXPERIMENTS; ENERGY TRANSFER DYE | PE CORPORATION | 2001-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220002716-A1 | TRINUCLEOTIDE CAP ANALOGS, PREPARATION AND USES THEREOF | RNGTT, RNMT, CPSF7 | AKR1B1 4453/4885 |
| US-20220143198-A1 | COMPOSITIONS AND METHODS RELATED TO TETHERED KETHOXAL DERIVATIVES | KLK3, ANXA6, CKMT1A; CKMT1B | AKR1B1 742/4885 |
| US-20210214773-A1 | COMPOSITIONS AND METHODS RELATED TO KETHOXAL DERIVATIVES | RNMT, PHAX, RNGTT | AKR1B1 1891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.