Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 8/20 | 0.36 |
| ▸ | ACACB | O00763 | 7/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31019945 | 0.85 | MC4R (0.44) | ACACBMAPT | |
| SCHEMBL31019938 | 0.83 | RORC (0.36) | RORCACACBNR1H2PIK3R1PIK3CA | |
| SCHEMBL30184847 | 0.80 | MC4R (0.44) | ACACB | |
| SCHEMBL24094563 | 0.80 | MC4R (0.44) | ACACB | |
| SCHEMBL24853356 | 0.80 | MC4R (0.44) | ACACB | |
| SCHEMBL24094586 | 0.80 | MC4R (0.44) | ACACB | |
| SCHEMBL30184853 | 0.80 | MC4R (0.44) | ACACB | |
| SCHEMBL30355177 | 0.80 | MC4R (0.44) | ACACB | |
| SCHEMBL31099083 | 0.78 | ACACB (0.39) | ACACB | |
| SCHEMBL31099068 | 0.78 | ACACB (0.39) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118515671-A | MC4R antagonist compound, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-08-20 | — | — | CN | disclosed |