Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 9/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 6/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31019940 | 0.83 | RORC (0.36) | RORCPIK3R1PIK3CAACACBNR1H2 | |
| SCHEMBL31019945 | 0.81 | MC4R (0.44) | ACACB | |
| SCHEMBL24853354 | 0.78 | ACACB (0.42) | GRM5ACACBNR1H2 | |
| SCHEMBL24094541 | 0.78 | ACACB (0.42) | GRM5ACACBNR1H2 | |
| SCHEMBL24094546 | 0.78 | ACACB (0.42) | GRM5ACACBNR1H2 | |
| SCHEMBL31099111 | 0.77 | ACACB (0.39) | DDB1CRBNGRM5ACACBNR1H2 | |
| SCHEMBL31099026 | 0.77 | ACACB (0.39) | DDB1CRBNGRM5ACACBNR1H2 | |
| SCHEMBL31099087 | 0.72 | CYP11B2 (0.39) | ACACBNR1H2 | |
| SCHEMBL31099041 | 0.69 | MC4R (0.41) | RORCACACBNR1H2 | |
| SCHEMBL5761360 | 0.68 | HTR2A (0.50) | SSTR4PIK3R1PIK3CAGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118515671-A | MC4R antagonist compound, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-08-20 | — | — | CN | disclosed |