Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 6/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | CD44 | P16070 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25244698 | 1.00 | PNMT (0.41) | PNMTHTR6CD44MAOBHTR2C | |
| SCHEMBL19684582 | 0.85 | PNMT (0.44) | PNMTHTR6CD44MAOBHTR2C | |
| SCHEMBL16402066 | 0.82 | CD44 (0.40) | PNMTCD44MAOBHTR2CADRA2A | |
| SCHEMBL30014809 | 0.82 | CD44 (0.40) | PNMTCD44MAOBHTR2CADRA2A | |
| SCHEMBL20439975 | 0.81 | HTR2C (0.44) | PNMTCD44MAOBHTR2CADRA2A | |
| SCHEMBL12968862 | 0.79 | ASIC3 (0.43) | PNMTHTR6CD44HTR2CASIC3 | |
| SCHEMBL29782809 | 0.78 | PNMT (0.46) | PNMTCD44MAOBHTR2CADRA2A | |
| SCHEMBL17699714 | 0.78 | PNMT (0.46) | PNMTCD44MAOBHTR2CADRA2A | |
| SCHEMBL20425892 | 0.78 | PNMT (0.50) | PNMTCD44MAOBHTR2CADRA2A | |
| SCHEMBL29507236 | 0.78 | PNMT (0.50) | PNMTCD44MAOBHTR2CADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119948023-A | Regulator containing piperidine polycyclic derivative, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-118451079-A | Benzopiperidine derivative modulators, methods of preparation and uses thereof | 上海翰森生物医药科技有限公司 | 2024-08-06 | — | — | CN | disclosed |