Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 2/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | HHAT | Q5VTY9 | 3/20 | 0.43 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22366344 | 1.00 | MTNR1B (0.48) | MTNR1BACETRPM8DRD1HHAT | |
| SCHEMBL28512675 | 0.86 | ACE (0.45) | ACECYP2D6NOTUMRIPK1 | |
| SCHEMBL9511054 | 0.83 | ACE (0.45) | MTNR1BACETRPM8DRD1HHAT | |
| SCHEMBL4032578 | 0.81 | ESR1 (0.51) | DRD1 | |
| SCHEMBL14575206 | 0.80 | NR1H2 (0.45) | MTNR1BACETRPM8DRD1 | |
| SCHEMBL2123936 | 0.80 | CAMK2A (0.43) | — | |
| SCHEMBL30997677 | 0.80 | NR1H2 (0.45) | MTNR1BACETRPM8DRD1 | |
| SCHEMBL20768178 | 0.80 | DPP4 (0.39) | CYP2D6NPSR1 | |
| SCHEMBL31546529 | 0.80 | CAMK2A (0.43) | — | |
| SCHEMBL3664252 | 0.80 | NR1H2 (0.45) | MTNR1BDRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119948023-A | Regulator containing piperidine polycyclic derivative, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-118451079-A | Benzopiperidine derivative modulators, methods of preparation and uses thereof | 上海翰森生物医药科技有限公司 | 2024-08-06 | — | — | CN | disclosed |