Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | PNMT | P11086 | 4/20 | 0.36 |
| ▸ | CD44 | P16070 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MELK | Q14680 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | HTR5A | P47898 | 3/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL330372 | 0.80 | ASIC3 (0.60) | ASIC3HTR2AHTR2CDRD2DRD3 | |
| SCHEMBL107103 | 0.79 | CYP1A2 (0.43) | ASIC3HTR2AHTR2CPNMTMELK | |
| Hydrochloric Acid SCHEMBL1000880 | 0.78 | ASIC3 (0.58) | ASIC3HTR2AHTR2CDRD2DRD3 | |
| Hydrochloric Acid SCHEMBL1266812 | 0.77 | CYP1A2 (0.42) | ASIC3HTR2AHTR2CPNMTMELK | |
| SCHEMBL30950592 | 0.77 | ASIC3 (0.47) | ASIC3HTR2AHTR2CDRD2DRD3 | |
| SCHEMBL1887809 | 0.77 | ASIC3 (0.47) | ASIC3HTR2AHTR2CDRD2DRD3 | |
| SCHEMBL420370 | 0.76 | PNMT (0.60) | HTR2AHTR2CDRD2DRD3PNMT | |
| SCHEMBL29741628 | 0.76 | PNMT (0.60) | HTR2AHTR2CDRD2DRD3PNMT | |
| Hydrochloric Acid SCHEMBL2315581 | 0.75 | CYP1A2 (0.41) | ASIC3HTR2AHTR2CPNMTMELK | |
| Hydrochloric Acid SCHEMBL29586555 | 0.74 | PNMT (0.58) | HTR2AHTR2CDRD2DRD3PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119948023-A | Regulator containing piperidine polycyclic derivative, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-118451079-A | Benzopiperidine derivative modulators, methods of preparation and uses thereof | 上海翰森生物医药科技有限公司 | 2024-08-06 | — | — | CN | disclosed |