SCHEMBL310203

SCHEMBL310203

Cc1cc(-c2cc(-c3ccc(N)c(C)c3)cc(-c3ccc(N)c(C)c3)c2)ccc1N

nearest known ligand 0.90

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 10/20 0.90
TDP1 Q9NUW8 9/20 0.90
ALDH1A1 P00352 9/20 0.90
TSHR P16473 5/20 0.90
TP53 P04637 3/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
HSD17B10 Q99714 4/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
KDM4E B2RXH2 2/20 0.44
MAPT P10636 2/20 0.44
PKM P14618 1/20 0.44
ALOX15 P16050 3/20 0.44
MAPK1 P28482 3/20 0.43
S100B P04271 1/20 0.43
APP P05067 1/20 0.42
SKP2 Q13309 1/20 0.42
HPGD P15428 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29764072 1.00 CYP3A4 (0.90) CYP3A4TDP1ALDH1A1TSHRTP53
Orthotolidine SCHEMBL49414 0.95 CYP3A4 (1.00) CYP3A4TDP1ALDH1A1TSHRTP53
Orthotolidine SCHEMBL29386552 0.95 CYP3A4 (1.00) CYP3A4TDP1ALDH1A1TSHRTP53
Orthotolidine SCHEMBL29365329 0.95 CYP3A4 (1.00) CYP3A4TDP1ALDH1A1TSHRTP53
Orthotolidine SCHEMBL2812115 0.92 CYP3A4 (0.94) CYP3A4TDP1ALDH1A1TSHRTP53
SCHEMBL8954009 0.92 CYP3A4 (0.94) CYP3A4TDP1ALDH1A1TSHRTP53
Orthotolidine SCHEMBL867121 0.92 CYP3A4 (0.94) CYP3A4TDP1ALDH1A1TSHRTP53
Orthotolidine SCHEMBL20547383 0.92 CYP3A4 (0.94) CYP3A4TDP1ALDH1A1TSHRTP53
Orthotolidine SCHEMBL22129692 0.92 CYP3A4 (0.94) CYP3A4TDP1ALDH1A1TSHRTP53
Orthotolidine SCHEMBL11189493 0.92 CYP3A4 (0.94) CYP3A4TDP1ALDH1A1TSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108137806-A Polyimide precursor, polyimide having crosslinked structure, and method for producing same 宇部兴产株式会社 2018-06-08 CN disclosed
EP-2714806-B1 THERMOPLASTIC MOULDING MATERIAL BASF SE (DE) 2015-07-08 EP disclosed
US-8987357-B2 Thermoplastic molding composition BASF SE (DE) 2015-03-24 US disclosed
US-20120302677-A1 THERMOPLASTIC MOLDING COMPOSITION BASF SE (DE) 2012-11-29 US disclosed
US-8093349-B2 Terminally modified polybranched polyimide, metal-plated terminally modified polybranched polyimide, and method for producing the same UBE INDUSTRIES, LTD. (JP) 2012-01-10 US disclosed
US-20100009206-A1 TERMINALLY MODIFIED POLYBRANCHED POLYIMIDE, METAL-PLATED TERMINALLY MODIFIED POLYBRANCHED POLYIMIDE, AND METHOD FOR PRODUCING THE SAME UBE INDUSTRIES, LTD. (JP) 2010-01-14 US disclosed