Orthotolidine

Orthotolidine

SCHEMBL29386552

Cc1cc(-c2ccc(N)c(C)c2)ccc1N

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 10/20 1.00
TDP1 Q9NUW8 9/20 1.00
ALDH1A1 P00352 9/20 1.00
TSHR P16473 5/20 1.00
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
HSD17B10 Q99714 4/20 0.48
ALOX15 P16050 3/20 0.48
MAPK1 P28482 3/20 0.48
TP53 P04637 3/20 0.48
SMN1; SMN2 Q16637 3/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
KDM4E B2RXH2 2/20 0.47
MAPT P10636 2/20 0.47
PKM P14618 1/20 0.47
S100B P04271 1/20 0.46
SKP2 Q13309 1/20 0.45
APP P05067 1/20 0.44
THRB P10828 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Orthotolidine SCHEMBL29365329 1.00 CYP3A4 (1.00) CYP3A4TDP1ALDH1A1TSHRMEN1
Orthotolidine SCHEMBL49414 1.00 CYP3A4 (1.00) CYP3A4TDP1ALDH1A1TSHRMEN1
Orthotolidine SCHEMBL867121 0.97 CYP3A4 (0.94) CYP3A4TDP1ALDH1A1TSHRMEN1
Orthotolidine SCHEMBL20547383 0.97 CYP3A4 (0.94) CYP3A4TDP1ALDH1A1TSHRMEN1
SCHEMBL8954009 0.97 CYP3A4 (0.94) CYP3A4TDP1ALDH1A1TSHRMEN1
Orthotolidine SCHEMBL11189493 0.97 CYP3A4 (0.94) CYP3A4TDP1ALDH1A1TSHRMEN1
Orthotolidine SCHEMBL2812115 0.97 CYP3A4 (0.94) CYP3A4TDP1ALDH1A1TSHRMEN1
Orthotolidine SCHEMBL22129692 0.97 CYP3A4 (0.94) CYP3A4TDP1ALDH1A1TSHRMEN1
Orthotolidine SCHEMBL6009632 0.97 CYP3A4 (0.94) CYP3A4TDP1ALDH1A1TSHRMEN1
Orthotolidine SCHEMBL38664709 0.97 CYP3A4 (0.94) CYP3A4TDP1ALDH1A1TSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026055875-A9 ONE-COMPONENT (1K) HEAT-ACTIVATABLE WATERBORNE POLYURETHANE ADHESIVE AND USE THEREOF HENKEL AG & CO. KGAA (DE) 2026-05-15 WO claimed
US-12529672-B2 Electrochemical sensor PALINTEST LIMITED (GB) 2026-01-20 US claimed
EP-4217720-B1 ELECTROCHEMICAL SENSOR PALINTEST LTD (GB) 2025-07-30 EP claimed
CN-116406396-B Polyamide imides 尤尼吉可株式会社 2024-03-26 CN claimed
US-20240044830-A1 ELECTROCHEMICAL SENSOR PALINTEST LIMITED (GB) 2024-02-08 US claimed
EP-4217720-A1 ELECTROCHEMICAL SENSOR Palintest Limited (GB) 2023-08-02 EP claimed
US-11379966-B1 Impurity detection system in continually running water through machine vision software JAIN ALISHA IYER (US) 2022-07-05 US claimed
US-20220207696-A1 Impurity Detection System in Continually Running Water through Machine Vision Software JAIN ALISHA IYER (US) 2022-06-30 US claimed
WO-2022064177-A1 ELECTROCHEMICAL SENSOR PALINTEST LIMITED (GB) 2022-03-31 WO claimed
WO-2026105423-A1 BINDER COMPOSITION FOR NONAQUEOUS SECONDARY BATTERY POSITIVE ELECTRODES, COMPOSITION FOR NONAQUEOUS SECONDARY BATTERY POSITIVE ELECTRODES, POSITIVE ELECTRODE FOR NONAQUEOUS SECONDARY BATTERIES, AND NONAQUEOUS SECONDARY BATTERY DIC株式会社 2026-05-21 WO disclosed
WO-2026055875-A9 ONE-COMPONENT (1K) HEAT-ACTIVATABLE WATERBORNE POLYURETHANE ADHESIVE AND USE THEREOF HENKEL AG & CO. KGAA (DE) 2026-05-15 WO disclosed
EP-3818371-B1 THIN FILM BULK ACOUSTIC WAVE PIEZOELECTRIC RESONATOR WITH INCREASED DYNAMIC RANGE ZOMEDICA BIOTECHNOLOGIES LLC (US) 2026-03-18 EP disclosed
US-20260029417-A1 STOOL SPECIMEN TEST DEVICE AND METHOD FOR STOOL SPECIMEN TEST EIKEN KAGAKU KABUSHIKI KAISHA (JP) 2026-01-29 US disclosed
US-20260029379-A1 BULK ACOUSTIC WAVE RESONATOR WITH INCREASED DYNAMIC RANGE ZOMEDICA BIOTECHNOLOGIES LLC (US) 2026-01-29 US disclosed
US-20220207696-A1 Impurity Detection System in Continually Running Water through Machine Vision Software JAIN ALISHA IYER (US) 2022-06-30 US disclosed
US-20220207696-A1 Impurity Detection System in Continually Running Water through Machine Vision Software JAIN ALISHA IYER (US) 2022-06-30 US disclosed
US-20220137021-A1 System and Method for Automatically Monitoring and Tracking the Chemistry of a Managed Body of Water ZIMA BRIAN (US) 2022-05-05 US disclosed
US-11319410-B2 Precursor for polyimide and use thereof ETERNAL MATERIALS CO., LTD. (TW) 2022-05-03 US disclosed
WO-2022064177-A1 ELECTROCHEMICAL SENSOR PALINTEST LIMITED (GB) 2022-03-31 WO disclosed
EP-3957604-A1 NITROGEN-BASED GAS SUSTAINED RELEASE AGENT, NITROGEN-BASED GAS SUSTAINED RELEASE BODY COMPRISING SAME, NITROGEN-BASED GAS SUSTAINED RELEASE METHOD USING SUSTAINED RELEASE BODY, BREATHING INSTRUMENT, WRAPPING BODY, AND SUSTAINED RELEASE DEVICE National Institute for Materials Science (JP) 2022-02-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260029379-A1 BULK ACOUSTIC WAVE RESONATOR WITH INCREASED DYNAMIC RANGE LIN28A, STUB1, L1CAM CYP3A4 3759/4885TDP1 2779/4885ALDH1A1 2091/4885
US-12529672-B2 Electrochemical sensor TPO, TET2, GPX4 CYP3A4 2228/4885TDP1 734/4885ALDH1A1 433/4885
US-20260029417-A1 STOOL SPECIMEN TEST DEVICE AND METHOD FOR STOOL SPECIMEN TEST APC, MUC1, ALPI CYP3A4 3475/4885TDP1 3195/4885ALDH1A1 413/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.