SCHEMBL310205

SCHEMBL310205

Nc1cc(Cl)c(S(N)(=O)=O)cc1S(N)(=O)=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 15/20 1.00
CA2 P00918 15/20 1.00
CA4 P22748 7/20 1.00
CA9 Q16790 7/20 1.00
CA12 O43570 6/20 1.00
CA6 P23280 6/20 1.00
CA5A P35218 6/20 1.00
CA7 P43166 6/20 1.00
CA14 Q9ULX7 6/20 1.00
CA5B Q9Y2D0 6/20 1.00
CA3 P07451 3/20 1.00
ALDH1A1 P00352 2/20 0.55
CA13 Q8N1Q1 3/20 0.50
CISD1 Q9NZ45 1/20 0.50
POLB P06746 1/20 0.50
APEX1 P27695 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
LMNA P02545 1/20 0.45
CYP2C9 P11712 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30659050 1.00 CA1 (1.00) CA1CA2CA4CA9CA12
SCHEMBL29376122 1.00 CA1 (1.00) CA1CA2CA4CA9CA12
Acetamide SCHEMBL25369769 0.89 CA1 (0.79) CA1CA2CA4CA9CA12
SCHEMBL1807804 0.88 CA1 (0.79) CA1CA2CA4CA9CA12
SCHEMBL11132234 0.88 CA1 (0.79) CA1CA2CA4CA9CA12
SCHEMBL9647910 0.88 CA1 (0.78) CA1CA2CA4CA9CA12
SCHEMBL27903562 0.88 CA1 (0.78) CA1CA2CA4CA9CA12
SCHEMBL26514797 0.88 CA1 (0.78) CA1CA2CA4CA9CA12
Hydrochloric Acid SCHEMBL11139867 0.86 CA1 (0.76) CA1CA2CA4CA9CA12
SCHEMBL1806519 0.86 CA1 (0.76) CA1CA2CA4CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1423 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118243799-A Detection method of valsartan hydrochlorothiazide related substances 珠海润都制药股份有限公司 2024-06-25 CN claimed
CN-114614058-B Thin-layer composite proton exchange membrane and preparation method and application thereof 中国石油化工股份有限公司 2024-05-07 CN claimed
CN-114369073-B Method for preparing high-purity hydrochlorothiazide 润都制药(荆门)有限公司 2024-03-26 CN claimed
CN-116769441-A Preparation method of underwear back button and product 广东启悦未来科技股份有限公司 2023-09-19 CN claimed
CN-114432903-B Composite membrane with acid resistance and preparation method and application thereof 中国石油化工股份有限公司 2023-03-14 CN claimed
EP-3670490-B1 METHOD OF PURIFYING PINE CHEMICAL COMPOSITIONS FROM ALDEHYDES KRATON POLYMERS LLC (US) 2023-01-18 EP claimed
CN-114614058-A Thin-layer composite proton exchange membrane and preparation method and application thereof 中国石油化工股份有限公司 2022-06-10 CN claimed
CN-114432903-A Composite membrane with acid resistance and preparation method and application thereof 中国石油化工股份有限公司 2022-05-06 CN claimed
CN-114369073-A Method for preparing high-purity hydrochlorothiazide 润都制药(荆门)有限公司 2022-04-19 CN claimed
CN-113588828-A Method for simultaneously detecting forty-eight stimulants in animal-derived food 西安市食品药品检验所(西安市药品不良反应监测中心) 2021-11-02 CN claimed
EP-1507813-A1 FAT BINDING USING INTER-POLYMER COMPLEX OF GLUCOSAMINE AND POLYACRYLIC ACID Ranbaxy Laboratories Limited (IN) 2005-02-23 EP claimed
EP-1385501-A2 PROBUCOL MONOESTERS AND THEIR USE TO INCREASE PLASMA HDL CHOLESTEROL LEVELS AND IMPROVE HDL FUNCTIONALITY Atherogenics, Inc. (US) 2004-02-04 EP claimed
WO-2003097714-A1 FAT BINDING USING INTER-POLYMER COMPLEX OF GLUCOSAMINE AND POLYACRYLIC ACID RANBAXY LABORATORIES LIMITED (IN) 2003-11-27 WO claimed
US-20030162824-A1 Methods of treating or preventing a cardiovascular condition using a cyclooxygenase-1 inhibitor PHARMACIA CORPORATION 2003-08-28 US claimed
EP-1336602-A1 Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases Scaramuzzino, Giovanni (IT) 2003-08-20 EP claimed
WO-2002087556-A9 PROBUCOL MONOESTERS AND THEIR USE TO INCREASE PLASMA HDL CHOLESTEROL LEVELS AND IMPROVE HDL FUNCTIONALITY ATHEROGENICS INC (US) 2003-03-20 WO claimed
WO-2002087556-A2 PROBUCOL MONOESTERS AND THEIR USE TO INCREASE PLASMA HDL CHOLESTEROL LEVELS AND IMPROVE HDL FUNCTIONALITY ATHEROGENICS, INC. (US) 2002-11-07 WO claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030162824-A1 Methods of treating or preventing a cardiovascular condition using a cyclooxygenase-1 inhibitor PTGS1, PTGIS, TNNT2 CA1 1067/4885CA2 217/4885CA4 1070/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.