Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 4/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 7/20 | 0.43 |
| ▸ | NPY4R | P50391 | 7/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.43 |
| ▸ | NPY1R | P25929 | 5/20 | 0.43 |
| ▸ | RAMP3 | O60896 | 6/20 | 0.43 |
| ▸ | CALCR | P30988 | 6/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30973966 | 0.83 | CAPN1 (0.46) | CAPN1CTSBXIAP | |
| SCHEMBL31518650 | 0.82 | XIAP (0.49) | CAPN1CTSBRAMP3CALCRNTSR1 | |
| SCHEMBL31366789 | 0.82 | OPRM1 (0.54) | NPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL30880891 | 0.82 | NTSR1 (0.48) | NPY2RNPY4RNPY5RNPY1RNTSR1 | |
| SCHEMBL29499664 | 0.81 | NPY2R (0.53) | NPY2RNPY4RNPY5RNPY1RRAMP3 | |
| SCHEMBL30666371 | 0.81 | CAPN1 (0.53) | CAPN1CTSBNPY2RNPY4RNPY5R | |
| SCHEMBL31226653 | 0.81 | XIAP (0.56) | CAPN1CTSBNPY2RNPY4RNPY5R | |
| SCHEMBL31462086 | 0.81 | CAPN1 (0.48) | CAPN1CTSBNPY2RNPY4RNPY5R | |
| SCHEMBL30974285 | 0.81 | CAPN1 (0.45) | CAPN1NPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL30275918 | 0.80 | CALCRL (0.47) | NPY2RNPY4RNPY5RNPY1RCALCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2847223-B2 | ANTI-B7-H6 ANTIBODY, FUSION PROTEINS, AND METHODS OF USING THE SAME | DARTMOUTH COLLEGE (US) | 2025-04-09 | — | — | EP | disclosed |
| US-20250002584-A1 | ANTI-B7-H6 ANTIBODY, FUSION PROTEINS, AND METHODS OF USING THE SAME | DARTMOUTH COLLEGE (US) | 2025-01-02 | — | — | US | disclosed |
| US-12065492-B2 | Anti-B7-H6 antibody, fusion proteins, and methods of using the same | THE TRUSTEES OF DARTMOUTH COLLEGE (US) | 2024-08-20 | — | — | US | disclosed |
| CN-110511278-B | Anti-B7-H6 antibodies, fusion proteins, and methods of use thereof | 达特茅斯大学理事会 | 2024-08-09 | — | — | CN | disclosed |