Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | FLT4 | P35916 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.31 |
| ▸ | TEK | Q02763 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16610769 | 0.83 | DGAT1 (0.39) | DGAT1EGFRIGF1RSRCFLT4 | |
| SCHEMBL27858492 | 0.79 | DGAT1 (0.36) | DGAT1EGFRIGF1RSRCFLT4 | |
| SCHEMBL31021711 | 0.78 | NPC1 (0.38) | DGAT1NPC1 | |
| SCHEMBL29112575 | 0.78 | DGAT1 (0.41) | DGAT1EGFRIGF1RSRCFLT4 | |
| SCHEMBL28929773 | 0.77 | DGAT1 (0.35) | DGAT1EGFRIGF1RSRCFLT4 | |
| SCHEMBL25254975 | 0.76 | KLKB1 (0.47) | DGAT1KLKB1NPC1PTPN1 | |
| SCHEMBL31021830 | 0.74 | DGAT1 (0.41) | DGAT1KLKB1PDE10A | |
| SCHEMBL29065501 | 0.74 | DGAT1 (0.44) | DGAT1PTPN1 | |
| SCHEMBL5767022 | 0.74 | CYP11B1 (0.40) | DGAT1 | |
| SCHEMBL5246675 | 0.74 | ALDH1A1 (0.43) | DGAT1EGFRIGF1RSRCFLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4655069-A1 | PYRIDAZINES AS SARM1 INHIBITORS | Disarm Therapeutics, Inc. (US) | 2025-12-03 | — | — | EP | disclosed |
| WO-2024158775-A1 | PYRIDAZINES AS SARM1 INHIBITORS | DISARM THERAPEUTICS, INC. (US) | 2024-08-02 | — | — | WO | disclosed |