Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30993737 | 0.70 | CHRNB2 (0.35) | CHRNB2CHRNA4KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9568939 | 0.68 | CHRNB2 (0.37) | CHRNB2CHRNA4ADORA1KDM4EALDH1A1 | |
| SCHEMBL9568946 | 0.67 | CHRNB2 (0.35) | CHRNB2CHRNA4ADORA1KDM4EALDH1A1 | |
| SCHEMBL12616854 | 0.67 | ADORA1 (0.37) | CHRNB2CHRNA4ADORA1KDM4EALDH1A1 | |
| SCHEMBL17621736 | 0.66 | CHRNB2 (0.35) | CHRNB2CHRNA4KDM4E | |
| Hydrochloric Acid SCHEMBL3105438 | 0.65 | KDM4E (0.39) | ADORA1KDM4EALDH1A1MAPTRAD52 | |
| SCHEMBL7163205 | 0.64 | CYP1A2 (0.38) | CHRNB2CHRNA4KDM4EALDH1A1MAPT | |
| SCHEMBL13598204 | 0.63 | CHRM5 (0.46) | ALDH1A1MAPTGAASMN1; SMN2MAOA | |
| SCHEMBL9568915 | 0.63 | CHRNB2 (0.54) | CHRNB2CHRNA4 | |
| Arecolon SCHEMBL1538394 | 0.63 | CHRNB2 (1.00) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130095-A9 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-08-02 | — | — | WO | disclosed |