Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30993557 | 0.87 | ALDH1A1 (0.44) | KDM4EALDH1A1SMN1; SMN2MAPTTSHR | |
| SCHEMBL26101898 | 0.80 | KDM4E (0.54) | KDM4EALDH1A1SMN1; SMN2MAPTTDP1 | |
| SCHEMBL31022969 | 0.76 | KDM4E (0.50) | KDM4EALDH1A1SMN1; SMN2MAPTTDP1 | |
| SCHEMBL23728533 | 0.73 | KDM4E (0.54) | KDM4EALDH1A1SMN1; SMN2MAPTTDP1 | |
| SCHEMBL30992926 | 0.72 | TP53 (0.44) | KDM4EALDH1A1SMN1; SMN2MAPTTSHR | |
| SCHEMBL18208953 | 0.71 | KDM4E (0.73) | KDM4EALDH1A1SMN1; SMN2MAPTTDP1 | |
| SCHEMBL18208179 | 0.71 | HPGD (0.70) | KDM4EALDH1A1SMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL1422926 | 0.69 | KDM4E (1.00) | KDM4EALDH1A1SMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL25117949 | 0.68 | KDM4E (0.54) | KDM4EALDH1A1SMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL19436670 | 0.67 | KDM4E (0.53) | KDM4EALDH1A1SMN1; SMN2MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130095-A9 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-08-02 | — | — | WO | disclosed |