Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GBA1 | P04062 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31023009 | 0.87 | KDM4E (0.53) | ALDH1A1USP2TSHRTP53THRB | |
| SCHEMBL30992926 | 0.85 | TP53 (0.44) | ALDH1A1USP2TSHRTP53THRB | |
| SCHEMBL9926694 | 0.71 | KDM4E (0.72) | ALDH1A1USP2TSHRHPGDKDM4E | |
| SCHEMBL2459547 | 0.70 | LMNA (0.57) | ALDH1A1USP2TSHRTP53THRB | |
| SCHEMBL29083850 | 0.68 | TP53 (0.60) | ALDH1A1TSHRTP53THRBLMNA | |
| SCHEMBL29083869 | 0.68 | KMT2A (0.60) | ALDH1A1TP53THRBLMNAKDM4E | |
| SCHEMBL19455445 | 0.67 | ALDH1A1 (0.64) | ALDH1A1USP2TSHRLMNAHPGD | |
| SCHEMBL25117949 | 0.66 | KDM4E (0.54) | ALDH1A1TSHRTP53HPGDKDM4E | |
| SCHEMBL2462654 | 0.65 | ALDH1A1 (0.63) | ALDH1A1USP2TSHRTP53LMNA | |
| SCHEMBL22343291 | 0.65 | TYK2 (0.77) | TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130095-A1 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-06-20 | — | — | WO | disclosed |