Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMAD3 | P84022 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | P4HB | P07237 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31023753 | 1.00 | SMAD3 (0.41) | SMAD3LTA4HP4HBHPGDALDH1A1 | |
| SCHEMBL31023932 | 0.86 | NPC1 (0.47) | SMAD3P4HBHPGDALDH1A1TSHR | |
| SCHEMBL31023723 | 0.83 | SMAD3 (0.42) | SMAD3P4HBHPGDALDH1A1MEN1 | |
| SCHEMBL31023906 | 0.82 | MGLL (0.36) | SMAD3P4HBALDH1A1TSHR | |
| SCHEMBL31023687 | 0.82 | MGLL (0.42) | SMAD3P4HBHPGD | |
| SCHEMBL31023960 | 0.78 | CYP3A4 (0.44) | SMAD3P4HBALDH1A1TSHRMEN1 | |
| SCHEMBL31023940 | 0.78 | HPGD (0.52) | SMAD3P4HBHPGDALDH1A1MEN1 | |
| SCHEMBL31023772 | 0.77 | P4HB (0.47) | SMAD3P4HBMEN1KMT2AOPRD1 | |
| SCHEMBL31023796 | 0.76 | CNR1 (0.38) | SMAD3P4HBHTTNPSR1 | |
| SCHEMBL17541495 | 0.73 | OGA (0.60) | LTA4HHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665718-A1 | SMALL MOLECULES AS MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS, COMPOSITIONS AND USE THEREOF | Apogee Pharmaceuticals, Inc. (CA) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024168426-A1 | SMALL MOLECULES AS MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS, COMPOSITIONS AND USE THEREOF | APOGEE PHARMACEUTICALS, INC. (CA) | 2024-08-22 | — | — | WO | disclosed |