Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CASP7 | P55210 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31024093 | 0.78 | TAAR1 (0.41) | MAPTSMN1; SMN2KMT2ALMNACYP3A4 | |
| SCHEMBL31024092 | 0.78 | BRD4 (0.52) | BRD4PIK3CGTP53MAPTKDM4E | |
| SCHEMBL25416819 | 0.78 | BRD4 (0.52) | BRD4PIK3CGTP53MAPTKDM4E | |
| SCHEMBL30943173 | 0.77 | TP53 (0.48) | BRD4TP53MAPTKDM4ENPC1 | |
| SCHEMBL23320411 | 0.77 | TP53 (0.48) | BRD4TP53MAPTKDM4ENPC1 | |
| SCHEMBL31024068 | 0.75 | PIK3CD (0.46) | PIK3CGTP53KDM4ENPC1ALDH1A1 | |
| SCHEMBL25417436 | 0.74 | KDR (0.49) | BRD4PIK3CGTP53MAPTKDM4E | |
| SCHEMBL31024064 | 0.72 | CYP2A6 (0.46) | PIK3CGNPC1ALDH1A1RAB9AMEN1 | |
| SCHEMBL31024053 | 0.72 | CYP2A6 (0.46) | PIK3CGNPC1ALDH1A1RAB9AMEN1 | |
| SCHEMBL23320368 | 0.71 | ALDH1A1 (0.48) | TP53MAPTKDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118475580-A | Platelet-derived growth factor receptor (PDGFR) alpha inhibitors and uses thereof | 普罗根托斯治疗公司 | 2024-08-09 | — | — | CN | disclosed |