Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25416819 | 1.00 | BRD4 (0.52) | BRD4XDHDYRK1ACLK4PIK3CG | |
| SCHEMBL25416514 | 0.84 | KDR (0.47) | XDHDYRK1ACLK4MAOBKDR | |
| SCHEMBL31024070 | 0.78 | BRD4 (0.49) | BRD4XDHDYRK1ACLK4PIK3CG | |
| SCHEMBL18338474 | 0.77 | DRD2 (0.45) | DYRK1ACLK4KDRKDM4EMAPT | |
| SCHEMBL25416101 | 0.76 | TAAR1 (0.44) | TP53CYP3A4NOTUM | |
| SCHEMBL12610026 | 0.75 | IDH1 (0.42) | DYRK1ACLK4MAOBKDRKDM4E | |
| SCHEMBL25417436 | 0.74 | KDR (0.49) | BRD4XDHDYRK1ACLK4PIK3CG | |
| SCHEMBL1180343 | 0.74 | ABL1 (0.69) | BRD4XDHDYRK1ACLK4MAOB | |
| SCHEMBL196765 | 0.74 | CYP3A4 (0.73) | BRD4XDHDYRK1ACLK4MAOB | |
| SCHEMBL29489425 | 0.74 | CYP3A4 (0.73) | BRD4XDHDYRK1ACLK4MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118475580-A | Platelet-derived growth factor receptor (PDGFR) alpha inhibitors and uses thereof | 普罗根托斯治疗公司 | 2024-08-09 | — | — | CN | disclosed |