Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 9/20 | 0.61 |
| ▸ | HTR6 | P50406 | 2/20 | 0.54 |
| ▸ | HTR1A | P08908 | 5/20 | 0.53 |
| ▸ | HTR2C | P28335 | 4/20 | 0.53 |
| ▸ | HTR2B | P41595 | 4/20 | 0.53 |
| ▸ | HTR1B | P28222 | 4/20 | 0.47 |
| ▸ | HTR1D | P28221 | 3/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | HTR1E | P28566 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | HTR5A | P47898 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | HTR1F | P30939 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31024311 | 0.89 | HTR2A (0.64) | HTR2AHTR6HTR1AHTR2CHTR2B | |
| SCHEMBL25790565 | 0.87 | HTR2A (0.76) | HTR2AHTR6HTR1AHTR2CHTR2B | |
| SCHEMBL25790684 | 0.87 | HTR2A (0.73) | HTR2AHTR6HTR1AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL31634311 | 0.86 | HTR2A (0.71) | HTR2AHTR6HTR1AHTR2CHTR2B | |
| SCHEMBL25792493 | 0.86 | HTR2A (0.78) | HTR2AHTR6HTR1AHTR2CHTR2B | |
| SCHEMBL25790560 | 0.86 | HTR2A (0.78) | HTR2AHTR6HTR1AHTR2CHTR2B | |
| SCHEMBL27219351 | 0.84 | HTR6 (0.70) | HTR2AHTR6HTR1AHTR2CHTR2B | |
| SCHEMBL31320737 | 0.84 | HTR2A (0.67) | HTR2AHTR6HTR1AHTR2CHTR2B | |
| SCHEMBL24994140 | 0.84 | HTR2A (0.78) | HTR2AHTR6HTR1AHTR2CHTR2B | |
| SCHEMBL31417453 | 0.83 | HTR2A (0.66) | HTR2AHTR6HTR1AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4655282-A1 | 3-(2-(DIMETHYLAMINO)ETHYL)-1H-INDOL-4-YL DERIVATIVES | COMPASS Pathfinder Limited (GB) | 2025-12-03 | — | — | EP | disclosed |
| US-20240269113-A1 | 3-(2-(DIMETHYLAMINO)ETHYL)-1H-INDOL-4-yl DERIVATIVES | COMPASS PATHFINDER LIMITED (GB) | 2024-08-15 | — | — | US | disclosed |
| WO-2024156732-A1 | 3-(2-(DIMETHYLAMINO)ETHYL)-1H-INDOL-4-YL DERIVATIVES | COMPASS PATHFINDER LIMITED (GB) | 2024-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240269113-A1 | 3-(2-(DIMETHYLAMINO)ETHYL)-1H-INDOL-4-yl DERIVATIVES | HTR2C, HTR2A, HTR1A | HTR2A 2/4885HTR6 6/4885HTR1A 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.