Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.66 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.66 |
| ▸ | CES2 | O00748 | 1/20 | 0.59 |
| ▸ | CES1 | P23141 | 1/20 | 0.59 |
| ▸ | MMP1 | P03956 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29987081 | 0.83 | PTPN1 (0.75) | GSK3BPTPN1CES2CES1MMP1 | |
| SCHEMBL26135918 | 0.83 | MMP1 (0.76) | GSK3BPTPN1CES2CES1MMP1 | |
| SCHEMBL11480265 | 0.82 | GSK3B (0.80) | GSK3BPTPN1CES1ALDH1A1TRPA1 | |
| SCHEMBL5509133 | 0.81 | HDAC1 (0.62) | GSK3BPTPN1CES2CES1MMP1 | |
| SCHEMBL1360049 | 0.81 | PTPN1 (0.68) | GSK3BPTPN1CES2CES1MMP1 | |
| SCHEMBL2074662 | 0.81 | PTPN1 (0.68) | GSK3BPTPN1CES2CES1MMP1 | |
| SCHEMBL5508790 | 0.80 | HDAC1 (0.65) | GSK3BPTPN1CES2CES1MMP1 | |
| SCHEMBL203931 | 0.79 | GSK3B (1.00) | GSK3BPTPN1CES2CES1MMP1 | |
| SCHEMBL2095082 | 0.79 | PTPN1 (0.66) | GSK3BPTPN1CES2CES1MMP1 | |
| SCHEMBL478183 | 0.79 | PTPN1 (0.66) | GSK3BPTPN1CES2CES1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365914-B1 | FLUORINE-CONTAINING ACETOPHENONES OPTIONALLY HALOGENATED IN THE CH3-GROUP, AND THEIR PREPARATION FROM FLUORINATED BENZONITRILES | BAYER AG (DE) | 1992-07-22 | — | — | EP | claimed |
| EP-3599854-B1 | PYRROLIDINONES AND A PROCESS TO PREPARE THEM | FMC CORP (US) | 2026-05-06 | — | — | EP | disclosed |
| CN-115504920-B | Pyrrolidone and preparation method thereof | FMC公司 | 2024-10-11 | — | — | CN | disclosed |
| CN-114539040-B | Method for synthesizing alpha-halogenated ketone compound by photocatalysis | 苏州大学张家港工业技术研究院 | 2023-06-23 | — | — | CN | disclosed |
| US-11560367-B2 | Pyrrolidinones and a process to prepare them | FMC CORPORATION (US) | 2023-01-24 | — | — | US | disclosed |
| CN-115504920-A | Pyrrolidone and preparation method thereof | FMC公司 | 2022-12-23 | — | — | CN | disclosed |
| CN-115368196-A | Selective method for preparing alpha-halogenated aryl ketone by titanium silicalite molecular sieve catalysis | 南京工业大学 | 2022-11-22 | — | — | CN | disclosed |
| CN-110691516-B | Pyrrolidone and preparation method thereof | FMC公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-114539040-A | Method for synthesizing alpha-haloketone compound by photocatalysis | 苏州大学张家港工业技术研究院 | 2022-05-27 | — | — | CN | disclosed |
| US-20210107890-A1 | PYRROLIDINONES AND A PROCESS TO PREPARE THEM | FMC CORPORATION | 2021-04-15 | — | — | US | disclosed |
| WO-1998032753-A1 | THIAZOLE BENZENESULFONAMIDES AS β3 AGONISTS FOR THE TREATMENT OF DIABETES AND OBESITY | MERCK & CO., INC. (US) | 1998-07-30 | — | — | WO | disclosed |
| EP-0780380-A1 | Triazole derivatives with antimycotic action and intermediates | SS PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0365913-B1 | Substituted 2-aminothiazoles | BAYER AG (DE) | 1993-11-18 | — | — | EP | disclosed |
| US-5142092-A | Chemical intermediate for making fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-25 | — | — | US | disclosed |
| EP-0365914-B1 | FLUORINE-CONTAINING ACETOPHENONES OPTIONALLY HALOGENATED IN THE CH3-GROUP, AND THEIR PREPARATION FROM FLUORINATED BENZONITRILES | BAYER AG (DE) | 1992-07-22 | — | — | EP | disclosed |
| US-5104879-A | ANTIMYCOTICALLY ACTIVE SUBSTITUTED 2-AMINOTHIAZOLES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-04-14 | — | — | US | disclosed |
| EP-0365914-A2 | Fluorine-containing acetophenones optionally halogenated in the CH3-group, and their preparation from fluorinated benzonitriles | BAYER AG (DE) | 1990-05-02 | — | — | EP | disclosed |
| EP-0365913-A2 | Substituted 2-aminothiazoles | BAYER AG (DE) | 1990-05-02 | — | — | EP | disclosed |
| US-4631280-A | Pyridazine derivatives having a psychotropic action, and medicaments in which they are present | SANOFI (FR) | 1986-12-23 | — | — | US | disclosed |
| US-4565814-A | Pyridazine derivatives having a psychotropic action and compositions | SANOFI (FR) | 1986-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210107890-A1 | PYRROLIDINONES AND A PROCESS TO PREPARE THEM | CCNB1, CCNA2, F2 | GSK3B 3310/4885PTPN1 3874/4885CES2 2709/4885 |
| US-11560367-B2 | Pyrrolidinones and a process to prepare them | CCNB1, CCNA2, F2 | GSK3B 3310/4885PTPN1 3874/4885CES2 2709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.