Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.66 |
| ▸ | GSK3B | P49841 | 2/20 | 0.66 |
| ▸ | CES2 | O00748 | 1/20 | 0.59 |
| ▸ | CES1 | P23141 | 1/20 | 0.59 |
| ▸ | MMP1 | P03956 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2269889 | 0.94 | MAPT (0.61) | PTPN1GSK3BCES2CES1MMP1 | |
| SCHEMBL6602154 | 0.85 | PTPN1 (0.62) | PTPN1GSK3BCES2CES1MMP1 | |
| SCHEMBL2764867 | 0.84 | MMP1 (0.62) | PTPN1GSK3BCES2CES1MMP1 | |
| SCHEMBL27787625 | 0.84 | PTPN1 (0.49) | PTPN1GSK3BCES2CES1MMP1 | |
| SCHEMBL26135918 | 0.83 | MMP1 (0.76) | PTPN1GSK3BCES2CES1MMP1 | |
| SCHEMBL29987081 | 0.83 | PTPN1 (0.75) | PTPN1GSK3BCES2CES1MMP1 | |
| SCHEMBL8051337 | 0.82 | SMN1; SMN2 (0.70) | GSK3BMAPTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL2634195 | 0.81 | HTR7 (0.66) | PTPN1GSK3BCES2CES1MMP1 | |
| SCHEMBL965418 | 0.81 | RAB9A (0.63) | MAPTALDH1A1SRD5A2SMN1; SMN2L3MBTL1 | |
| SCHEMBL2074662 | 0.81 | PTPN1 (0.68) | PTPN1GSK3BCES2CES1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 250 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108083999-B | Green preparation method of alpha-hydroxyketone | 西北师范大学 | 2020-08-11 | — | — | CN | claimed |
| US-9201318-B2 | Polymer for charge generation layer and charge transport layer formulation | XEROX CORPORATION (US) | 2015-12-01 | — | — | US | claimed |
| US-20150024310-A1 | POLYMER FOR CHARGE GENERATION LAYER AND CHARGE TRANSPORT LAYER FORMULATION | XEROX CORPORATION | 2015-01-22 | — | — | US | claimed |
| US-8877413-B2 | Flexible imaging members comprising improved ground strip | XEROX CORPORATION (US) | 2014-11-04 | — | — | US | claimed |
| US-8614038-B2 | Plasticized anti-curl back coating for flexible imaging member | XEROX CORPORATION (US) | 2013-12-24 | — | — | US | claimed |
| US-20130216266-A1 | IMAGING MEMBERS COMPRISING FLUOROKETONE | XEROX CORPORATION (US) | 2013-08-22 | — | — | US | claimed |
| US-20130202995-A1 | PLASTICIZED ANTI-CURL BACK COATING FOR FLEXIBLE IMAGING MEMBER | XEROX CORPORATION (US) | 2013-08-08 | — | — | US | claimed |
| US-20130052576-A1 | FLEXIBLE IMAGING MEMBERS COMPRISING IMPROVED GROUND STRIP | XEROX CORPORATION (US) | 2013-02-28 | — | — | US | claimed |
| US-8343700-B2 | Imaging members having stress/strain free layers | XEROX CORPORATION (US) | 2013-01-01 | — | — | US | claimed |
| US-8232030-B2 | Curl-free imaging members with a slippery surface | XEROX CORPORATION (US) | 2012-07-31 | — | — | US | claimed |
| US-20110256474-A1 | IMAGING MEMBERS HAVING STRESS/STRAIN FREE LAYERS | XEROX CORPORATION (US) | 2011-10-20 | — | — | US | claimed |
| US-20110229808-A1 | CURL-FREE IMAGING MEMBERS WITH A SLIPPERY SURFACE | XEROX CORPORATION (US) | 2011-09-22 | — | — | US | claimed |
| US-20110136049-A1 | IMAGING MEMBERS COMPRISING FLUOROKETONE | XEROX CORPORATION (US) | 2011-06-09 | — | — | US | claimed |
| JP-1019033-A | — | — | None | — | — | JP | disclosed |
| JP-11343259-A | — | — | None | — | — | JP | disclosed |
| US-12486218-B2 | Compounds advantageous in the treatment of central nervous system diseases and disorders | AURIMMED PHARMA, INC. (US) | 2025-12-02 | — | — | US | disclosed |
| EP-0158448-A2 | Azolyl propanols | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-10-16 | — | — | EP | disclosed |
| EP-0092239-A2 | Oxazole derivatives, production and use thereof | Takeda Chemical Industries, Ltd. (JP) | 1983-10-26 | — | — | EP | disclosed |
| US-4293552-A | Novel 1-(mono-o-substituted benzoyl)-3-(substituted pyrazinyl) ureas | ELI LILLY AND COMPANY (US) | 1981-10-06 | — | — | US | disclosed |
| US-4160834-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1979-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12486218-B2 | Compounds advantageous in the treatment of central nervous system diseases and disorders | SMN1; SMN2, HDAC6, CTSA | PTPN1 3902/4885GSK3B 45/4885CES2 404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.