SCHEMBL31025910

SCHEMBL31025910

Cc1c(C(=O)O)[nH]c2cc(C(F)(F)F)ccc12

nearest known ligand 0.64

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.55
GPR35 Q9HC97 1/20 0.53
KIF11 P52732 7/20 0.53
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
ALDH1A1 P00352 1/20 0.50
CYP1A2 P05177 1/20 0.50
HPGD P15428 1/20 0.50
ALOX12 P18054 1/20 0.50
MPL P40238 2/20 0.49
CA12 O43570 1/20 0.49
CA9 Q16790 1/20 0.49
MAPK1 P28482 1/20 0.47
MAP2K4 P45985 1/20 0.47
MAPK6 Q16659 1/20 0.47
MAPKAPK5 Q8IW41 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4616764 0.88 KMT2A (0.64) MAPTGPR35KIF11MEN1KMT2A
SCHEMBL31025893 0.86 KIF11 (0.58) MAPTGPR35KIF11MEN1KMT2A
SCHEMBL2975736 0.83 KIF11 (0.48) MAPTKIF11MEN1KMT2ACA12
SCHEMBL4333061 0.83 KIF11 (0.54) MAPTGPR35KIF11MEN1KMT2A
SCHEMBL28780 0.82 MAPT (0.54) MAPTKIF11MEN1KMT2AALDH1A1
Guanidine SCHEMBL8688379 0.80 KMT2A (0.56) MAPTGPR35KIF11MEN1KMT2A
SCHEMBL31025889 0.79 EGFR (0.59) GPR35KIF11MEN1KMT2AALDH1A1
SCHEMBL9583726 0.78 KIF11 (0.47) MAPTGPR35KIF11MEN1KMT2A
SCHEMBL1144752 0.78 MEN1 (0.54) MAPTKIF11MEN1KMT2AALDH1A1
SCHEMBL31025911 0.78 KIF11 (0.52) MAPTKIF11MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4660193-A1 INDOLE COMPOUND DECOMPOSING IKZF2, AND USE THEREOF Korea Research Institute of Chemical Technology (KR) 2025-12-10 EP disclosed
WO-2024162746-A1 INDOLE COMPOUND DECOMPOSING IKZF2, AND USE THEREOF 한국화학연구원 2024-08-08 WO disclosed