SCHEMBL31025911

SCHEMBL31025911

Cc1c(C(=O)O)[nH]c2cc(OC(F)(F)F)ccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.52
GPR17 Q13304 2/20 0.46
PTGS2 P35354 2/20 0.45
PTGS1 P23219 1/20 0.45
IDO1 P14902 1/20 0.44
TDO2 P48775 1/20 0.44
KDM4E B2RXH2 5/20 0.44
ALDH1A1 P00352 3/20 0.44
MAPT P10636 2/20 0.44
HPGD P15428 2/20 0.44
GAA P10253 2/20 0.44
USP2 O75604 1/20 0.44
ALOX15 P16050 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
HSD17B10 Q99714 1/20 0.44
RHEB Q15382 2/20 0.44
GSK3B P49841 1/20 0.42
RUNX1 Q01196 1/20 0.42
EGLN1 Q9GZT9 1/20 0.42
NPC1 O15118 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2494500 0.86 EIF4A3 (0.55) KIF11GPR17PTGS2PTGS1IDO1
SCHEMBL1144751 0.82 GPR17 (0.64) GPR17PTGS2KDM4EALDH1A1MAPT
SCHEMBL9662514 0.81 PTGS2 (0.54) KIF11GPR17PTGS2PTGS1KDM4E
SCHEMBL9661003 0.81 GPR17 (0.48) GPR17PTGS2PTGS1ALDH1A1ALOX15
SCHEMBL9185752 0.79 GPR17 (0.72) GPR17KDM4EALDH1A1HPGDHSD17B10
SCHEMBL31025910 0.78 MAPT (0.55) KIF11ALDH1A1MAPTHPGDKMT2A
SCHEMBL28207448 0.76 KIF11 (0.51) KIF11PTGS2PTGS1IDO1TDO2
SCHEMBL6333942 0.76 KDM4E (0.57) KIF11IDO1TDO2KDM4EALDH1A1
SCHEMBL2643401 0.76 CYP2C9 (0.60) PTGS2PTGS1KDM4EALDH1A1MAPT
SCHEMBL31025889 0.75 EGFR (0.59) KIF11GPR17PTGS2PTGS1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4660193-A1 INDOLE COMPOUND DECOMPOSING IKZF2, AND USE THEREOF Korea Research Institute of Chemical Technology (KR) 2025-12-10 EP disclosed
WO-2024162746-A1 INDOLE COMPOUND DECOMPOSING IKZF2, AND USE THEREOF 한국화학연구원 2024-08-08 WO disclosed