SCHEMBL31025919

SCHEMBL31025919

Cc1c(C(=O)O)[nH]c2c(F)c(N3CCN(C)CC3)ccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.46
DRD4 P21917 1/20 0.46
DRD3 P35462 1/20 0.46
KDM4E B2RXH2 3/20 0.41
ALDH1A1 P00352 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
POLB P06746 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
HTT P42858 1/20 0.41
RECQL P46063 1/20 0.41
MCL1 Q07820 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
WDR5 P61964 6/20 0.39
HRH4 Q9H3N8 3/20 0.38
ALK Q9UM73 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31025897 0.86 ALDH1A1 (0.43) KDM4EALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL31025887 0.75 ALDH1A1 (0.47) DRD3KDM4EALDH1A1MEN1KMT2A
SCHEMBL31025918 0.73 GPR17 (0.62) KDM4EALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL31025905 0.70 MCL1 (0.44) KDM4EALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL27482515 0.67 ALDH1A1 (0.43) DRD2DRD4DRD3KDM4EALDH1A1
SCHEMBL3436293 0.67 ALDH1A1 (0.49) DRD2DRD4DRD3KDM4EALDH1A1
SCHEMBL3255112 0.67 MCL1 (0.54) KDM4EALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL32691697 0.67 KDM4E (0.50) DRD2DRD4DRD3KDM4EALDH1A1
SCHEMBL22471212 0.66 ALDH1A1 (0.58) KDM4EALDH1A1L3MBTL1KMT2APOLB
SCHEMBL30464713 0.66 ALDH1A1 (0.58) KDM4EALDH1A1L3MBTL1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4660193-A1 INDOLE COMPOUND DECOMPOSING IKZF2, AND USE THEREOF Korea Research Institute of Chemical Technology (KR) 2025-12-10 EP disclosed
WO-2024162746-A1 INDOLE COMPOUND DECOMPOSING IKZF2, AND USE THEREOF 한국화학연구원 2024-08-08 WO disclosed