SCHEMBL31025905

SCHEMBL31025905

Cc1c(C(=O)O)[nH]c2c(F)c(C#N)ccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 2/20 0.44
MEN1 O00255 2/20 0.44
ALDH1A1 P00352 2/20 0.44
POLB P06746 2/20 0.44
KMT2A Q03164 2/20 0.44
KDM4E B2RXH2 1/20 0.44
GAA P10253 1/20 0.44
MAPT P10636 1/20 0.44
HPGD P15428 1/20 0.44
TSHR P16473 1/20 0.44
HTT P42858 1/20 0.44
RECQL P46063 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
NOTUM Q6P988 1/20 0.40
GPR17 Q13304 4/20 0.39
GPR35 Q9HC97 2/20 0.37
EIF4A3 P38919 2/20 0.37
AR P10275 1/20 0.35
RPA1 P27694 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31025918 0.77 GPR17 (0.62) MCL1MEN1ALDH1A1POLBKMT2A
SCHEMBL3455993 0.74 NOTUM (0.49) NOTUMAR
SCHEMBL3255112 0.74 MCL1 (0.54) MCL1MEN1ALDH1A1POLBKMT2A
SCHEMBL31025884 0.71 ALDH1A1 (0.43) MEN1ALDH1A1POLBKMT2AKDM4E
SCHEMBL4090402 0.70 MCL1 (0.62) MCL1MEN1ALDH1A1POLBKMT2A
SCHEMBL31025919 0.70 DRD2 (0.46) MCL1MEN1ALDH1A1POLBKMT2A
SCHEMBL31025897 0.69 ALDH1A1 (0.43) MCL1MEN1ALDH1A1POLBKMT2A
SCHEMBL3457412 0.68 NOTUM (0.46) KDM4ENOTUMAR
SCHEMBL31025915 0.68 CSNK2A2 (0.53) MCL1MEN1ALDH1A1POLBKMT2A
SCHEMBL2724485 0.68 RXRA (0.40) SMN1; SMN2NOTUMAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4660193-A1 INDOLE COMPOUND DECOMPOSING IKZF2, AND USE THEREOF Korea Research Institute of Chemical Technology (KR) 2025-12-10 EP disclosed
WO-2024162746-A1 INDOLE COMPOUND DECOMPOSING IKZF2, AND USE THEREOF 한국화학연구원 2024-08-08 WO disclosed