SCHEMBL31025925

SCHEMBL31025925

Cc1c(C(=O)O)[nH]c2c(Cl)c(Cl)ccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.50
MCL1 Q07820 2/20 0.50
MEN1 O00255 2/20 0.50
ALDH1A1 P00352 2/20 0.50
POLB P06746 2/20 0.50
KMT2A Q03164 2/20 0.50
KDM4E B2RXH2 1/20 0.50
GAA P10253 1/20 0.50
HPGD P15428 1/20 0.50
TSHR P16473 1/20 0.50
HTT P42858 1/20 0.50
RECQL P46063 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
CSNK2A2 P19784 2/20 0.47
CSNK2B P67870 2/20 0.47
CSNK2A1 P68400 2/20 0.47
GPR17 Q13304 1/20 0.43
GPR35 Q9HC97 2/20 0.41
PARP14 Q460N5 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31025915 0.88 CSNK2A2 (0.53) MAPTMCL1MEN1ALDH1A1POLB
SCHEMBL31025918 0.83 GPR17 (0.62) MAPTMCL1MEN1ALDH1A1POLB
SCHEMBL4046879 0.82 ALDH1A1 (0.48) MAPTMEN1ALDH1A1KMT2AKDM4E
SCHEMBL26912401 0.81 CSNK2A2 (0.46) TSHRCSNK2A2CSNK2BCSNK2A1GPR17
SCHEMBL4076852 0.79 KDM4E (0.62) MAPTMCL1MEN1ALDH1A1POLB
SCHEMBL3255112 0.77 MCL1 (0.54) MAPTMCL1MEN1ALDH1A1POLB
SCHEMBL14739118 0.75 GPR17 (0.76) ALDH1A1KDM4EGPR17
SCHEMBL19330991 0.75 GPR17 (0.44) MCL1MEN1ALDH1A1POLBKMT2A
SCHEMBL8321684 0.75 MEN1 (0.43) MAPTMCL1MEN1ALDH1A1POLB
SCHEMBL4363402 0.72 GRIN1 (0.44) MAPTMCL1MEN1ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4660193-A1 INDOLE COMPOUND DECOMPOSING IKZF2, AND USE THEREOF Korea Research Institute of Chemical Technology (KR) 2025-12-10 EP disclosed
WO-2024162746-A1 INDOLE COMPOUND DECOMPOSING IKZF2, AND USE THEREOF 한국화학연구원 2024-08-08 WO disclosed