Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAP2 | P11137 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 2/20 | 0.41 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8687603 | 0.88 | MAP2 (0.41) | GRIN1KDM4EMEN1ALDH1A1GAA | |
| SCHEMBL16570960 | 0.83 | GPR35 (0.50) | MCL1KDM4EMEN1ALDH1A1POLB | |
| SCHEMBL4076852 | 0.76 | KDM4E (0.62) | MCL1KDM4EMEN1ALDH1A1POLB | |
| SCHEMBL7532885 | 0.75 | GPR17 (0.58) | GRIN1MEN1HPGDTSHRKMT2A | |
| SCHEMBL31025915 | 0.74 | CSNK2A2 (0.53) | MCL1KDM4EMEN1ALDH1A1POLB | |
| SCHEMBL3037898 | 0.72 | MAP2 (0.63) | MEN1ALDH1A1POLBGAAMAPT | |
| SCHEMBL31025925 | 0.72 | MAPT (0.50) | MCL1KDM4EMEN1ALDH1A1POLB | |
| SCHEMBL3110609 | 0.71 | MAPT (0.46) | GRIN1MCL1KDM4EMEN1ALDH1A1 | |
| SCHEMBL30182439 | 0.71 | MAPT (0.46) | GRIN1MCL1KDM4EMEN1ALDH1A1 | |
| SCHEMBL31025927 | 0.71 | MEN1 (0.50) | GRIN1MEN1ALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009063495-A2 | SUBSTITUTED INDOLE AND ITS DERIVATIVES AS CANNABINOID MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2009-05-22 | — | — | WO | claimed |