Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | CNR1 | P21554 | 5/20 | 0.61 |
| ▸ | VDR | P11473 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 6/20 | 0.50 |
| ▸ | MGAM | O43451 | 5/20 | 0.50 |
| ▸ | SI | P14410 | 5/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 5/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31026315 | 0.88 | MAPT (0.55) | MAPTNPSR1KMT2AMEN1POLB | |
| SCHEMBL31026329 | 0.86 | MAPT (0.53) | MAPTNPSR1KMT2AMEN1POLB | |
| SCHEMBL31026322 | 0.86 | MAPT (0.56) | MAPTNPSR1KMT2AMEN1POLB | |
| SCHEMBL7010866 | 0.83 | MEN1 (0.82) | MAPTNPSR1KMT2AMEN1POLB | |
| SCHEMBL31026312 | 0.80 | KMT2A (0.65) | MAPTNPSR1KMT2AMEN1POLB | |
| SCHEMBL27663389 | 0.79 | VDR (0.58) | MAPTNPSR1KMT2AMEN1POLB | |
| SCHEMBL9484344 | 0.79 | MEN1 (0.63) | MAPTNPSR1KMT2AMEN1POLB | |
| SCHEMBL7012422 | 0.78 | MEN1 (0.77) | MAPTNPSR1KMT2AMEN1POLB | |
| SCHEMBL31026323 | 0.78 | MEN1 (0.77) | MAPTNPSR1KMT2AMEN1POLB | |
| SCHEMBL31026318 | 0.78 | MEN1 (0.77) | MAPTNPSR1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118420514-A | Method for synthesizing 3- (2-nitro-1-aryl) -1H-indole derivative by using cyclopentadienyl titanium/Bronsted acid in synergistic catalysis mode | 宁夏师范学院 | 2024-08-02 | — | — | CN | disclosed |