Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.82 |
| ▸ | POLB | P06746 | 2/20 | 0.82 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
| ▸ | MGAM | O43451 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | SI | P14410 | 3/20 | 0.57 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.57 |
| ▸ | CNR1 | P21554 | 8/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7012422 | 0.91 | MEN1 (0.77) | MEN1KMT2APOLBMAPTNPSR1 | |
| SCHEMBL31026318 | 0.91 | MEN1 (0.77) | MEN1KMT2APOLBMAPTNPSR1 | |
| SCHEMBL31026323 | 0.91 | MEN1 (0.77) | MEN1KMT2APOLBMAPTNPSR1 | |
| SCHEMBL31026312 | 0.87 | KMT2A (0.65) | MEN1KMT2APOLBMAPTNPSR1 | |
| SCHEMBL7014720 | 0.87 | MEN1 (0.76) | MEN1KMT2APOLBMAPTNPSR1 | |
| SCHEMBL7011766 | 0.87 | KMT2A (0.72) | MEN1KMT2APOLBMAPTNPSR1 | |
| SCHEMBL31026314 | 0.83 | MAPT (0.70) | MEN1KMT2APOLBMAPTNPSR1 | |
| SCHEMBL9484344 | 0.83 | MEN1 (0.63) | MEN1KMT2APOLBMAPTNPSR1 | |
| SCHEMBL17645107 | 0.82 | MEN1 (0.58) | MEN1KMT2APOLBMAPTNPSR1 | |
| SCHEMBL17645108 | 0.82 | MEN1 (0.58) | MEN1KMT2APOLBMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10377711-B2 | Cannabinoid type 1 receptor modulators | THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) | 2019-08-13 | — | — | US | disclosed |
| US-10246414-B2 | Allosteric modulators of CB1 cannabinoid receptors | NORTHEASTERN UNIVERSITY (US) | 2019-04-02 | — | — | US | disclosed |
| EP-2800569-B1 | ALLOSTERIC MODULATORS OF CB1 CANNABINOID RECEPTORS | UNIV NORTHEASTERN (US) | 2018-07-25 | — | — | EP | disclosed |
| US-20180118681-A1 | CANNABINOID TYPE 1 RECEPTOR MODULATORS | THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) | 2018-05-03 | — | — | US | disclosed |
| US-20170197918-A1 | Allosteric Modulators of CB1 Cannabinoid Receptors | NORTHEASTERN UNIVERSITY | 2017-07-13 | — | — | US | disclosed |
| US-20170197918-A1 | Allosteric Modulators of CB1 Cannabinoid Receptors | NORTHEASTERN UNIVERSITY | 2017-07-13 | — | — | US | disclosed |
| US-20170197918-A1 | Allosteric Modulators of CB1 Cannabinoid Receptors | NORTHEASTERN UNIVERSITY | 2017-07-13 | — | — | US | disclosed |
| US-9556118-B2 | Allosteric modulators of CB1 cannabinoid receptors | NORTHEASTERN UNIVERSITY (US) | 2017-01-31 | — | — | US | disclosed |
| US-9556118-B2 | Allosteric modulators of CB1 cannabinoid receptors | NORTHEASTERN UNIVERSITY (US) | 2017-01-31 | — | — | US | disclosed |
| US-9556118-B2 | Allosteric modulators of CB1 cannabinoid receptors | NORTHEASTERN UNIVERSITY (US) | 2017-01-31 | — | — | US | disclosed |
| CN-101962366-A | Diphenyl thioether linked bis-imidazoline ligand compound and preparation method thereof | BEIJING INST TECHNOLOGY | 2011-02-02 | — | — | CN | disclosed |
| US-20100189648-A1 | INHIBITORS FOR DISRUPTING THE INTERACTION OF UBIQUITINATION RELATED ENZYMES AND USES THEREOF | HUANG LAN | 2010-07-29 | — | — | US | disclosed |
| US-20100189648-A1 | INHIBITORS FOR DISRUPTING THE INTERACTION OF UBIQUITINATION RELATED ENZYMES AND USES THEREOF | HUANG LAN | 2010-07-29 | — | — | US | disclosed |
| CN-101768118-A | Bi-imidazoline diphenylamine compound and preparation method thereof | UNIV BEIJING | 2010-07-07 | — | — | CN | disclosed |
| CN-101585834-A | Preparation and use of aromatic heterocyclic methylene BOZ | UNIV CHINA AGRICULTURAL (CN) | 2009-11-25 | — | — | CN | disclosed |
| WO-2008052441-A1 | INHIBITORS FOR DISRUPTING THE INTERACTION OF UBIQUITINATION RELATED ENZYMES AND USES THEREOF | HUANG LAN (US) | 2008-05-08 | — | — | WO | disclosed |
| EP-0923581-B1 | 4-SUBSTITUTED BETA-CARBOLINES AS IMMUNOMODULATORS | BOEHRINGER INGELHEIM PHARMA (US) | 2003-05-21 | — | — | EP | disclosed |
| US-6093723-A | AN IMMUNOMODULATOR FOR TREATING AND PREVENTING IMMUNE DISORDERS, INCLUDING AUTOIMMUNE DISEASE, INFLAMMATORY DISEASE, ORGAN TRANSPLANT REJECTION AND OTHER DISORDERS ASSOCIATED WITH IL-2 MEDIATED IMMUNE RESPONSE | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2000-07-25 | — | — | US | disclosed |
| EP-0923581-A1 | 4-SUBSTITUTED BETA-CARBOLINES AS IMMUNOMODULATORS | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998006719-A1 | 4-SUBSTITUTED BETA-CARBOLINES AS IMMUNOMODULATORS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1998-02-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118681-A1 | CANNABINOID TYPE 1 RECEPTOR MODULATORS | CNR1, CNR2, GPR18 | MEN1 3818/4885KMT2A 3294/4885POLB 4442/4885 |
| US-10246414-B2 | Allosteric modulators of CB1 cannabinoid receptors | CNR1, CNR2, GPR18 | MEN1 4653/4885KMT2A 2580/4885POLB 4481/4885 |
| US-10377711-B2 | Cannabinoid type 1 receptor modulators | CNR1, CNR2, GPR18 | MEN1 3818/4885KMT2A 3294/4885POLB 4442/4885 |
| US-20100189648-A1 | INHIBITORS FOR DISRUPTING THE INTERACTION OF UBIQUITINATION RELATED ENZYMES AND USES THEREOF | MDM2, UBE2N, UBE2E1 | MEN1 3921/4885KMT2A 795/4885POLB 2133/4885 |
| US-20170197918-A1 | Allosteric Modulators of CB1 Cannabinoid Receptors | CNR1, CNR2, GPR18 | MEN1 4653/4885KMT2A 2580/4885POLB 4481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.