Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | FURIN | P09958 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27510 | 0.97 | ALDH1A1 (0.59) | ALDH1A1TSHRL3MBTL1ATMTDP1 | |
| Benzene SCHEMBL9243917 | 0.94 | ALDH1A1 (0.57) | ALDH1A1TSHRL3MBTL1ATMTDP1 | |
| Hydrogen Sulfide SCHEMBL10899463 | 0.94 | ALDH1A1 (0.57) | ALDH1A1TSHRL3MBTL1ATMTDP1 | |
| Iodide SCHEMBL29916276 | 0.94 | ALDH1A1 (0.57) | ALDH1A1TSHRL3MBTL1ATMTDP1 | |
| Hydrochloric Acid SCHEMBL8084573 | 0.94 | ALDH1A1 (0.57) | ALDH1A1TSHRL3MBTL1ATMTDP1 | |
| SCHEMBL7789337 | 0.92 | ALDH1A1 (0.55) | ALDH1A1TSHRL3MBTL1ATMTDP1 | |
| SCHEMBL4349236 | 0.90 | ATM (0.65) | ALDH1A1TSHRL3MBTL1ATMTDP1 | |
| Isophthalic Acid SCHEMBL10423199 | 0.87 | CA12 (0.58) | ALDH1A1TSHRL3MBTL1ATMTDP1 | |
| SCHEMBL3796206 | 0.87 | CA12 (0.58) | ALDH1A1TSHRL3MBTL1ATMTDP1 | |
| SCHEMBL12501820 | 0.87 | CA12 (0.58) | ALDH1A1TSHRL3MBTL1ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118653224-A | Polyimide fiber and preparation method thereof | 长春高琦聚酰亚胺材料有限公司 | 2024-09-17 | — | — | CN | claimed |
| CN-118653305-A | Composite polyimide fiber and preparation method thereof | 长春高琦聚酰亚胺材料有限公司 | 2024-09-17 | — | — | CN | claimed |
| CN-118638310-A | Polyimide powder, preparation method thereof and thermoplastic plastic | 长春高琦聚酰亚胺材料有限公司 | 2024-09-13 | — | — | CN | claimed |
| CN-118653224-A | Polyimide fiber and preparation method thereof | 长春高琦聚酰亚胺材料有限公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-118653305-A | Composite polyimide fiber and preparation method thereof | 长春高琦聚酰亚胺材料有限公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-118638310-A | Polyimide powder, preparation method thereof and thermoplastic plastic | 长春高琦聚酰亚胺材料有限公司 | 2024-09-13 | — | — | CN | disclosed |