Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 known ✓ | P09874 | 2/20 | 0.43 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.41 |
| ▸ | HDAC8 known ✓ | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 known ✓ | Q9UBN7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | FURIN | P09958 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27510 | 0.97 | ALDH1A1 (0.59) | ALDH1A1TSHRL3MBTL1ATMTDP1 | |
| Benzene SCHEMBL9243917 | 0.94 | ALDH1A1 (0.57) | ALDH1A1TSHRL3MBTL1ATMTDP1 | |
| Hydrogen Sulfide SCHEMBL10899463 | 0.94 | ALDH1A1 (0.57) | ALDH1A1TSHRL3MBTL1ATMTDP1 | |
| Bromide SCHEMBL31026552 | 0.94 | ALDH1A1 (0.57) | ALDH1A1TSHRL3MBTL1ATMTDP1 | |
| Iodide SCHEMBL29916276 | 0.94 | ALDH1A1 (0.57) | ALDH1A1TSHRL3MBTL1ATMTDP1 | |
| SCHEMBL7789337 | 0.92 | ALDH1A1 (0.55) | ALDH1A1TSHRL3MBTL1ATMTDP1 | |
| SCHEMBL4349236 | 0.90 | ATM (0.65) | ALDH1A1TSHRL3MBTL1ATMTDP1 | |
| SCHEMBL3796206 | 0.87 | CA12 (0.58) | ALDH1A1TSHRL3MBTL1ATMTDP1 | |
| Isophthalic Acid SCHEMBL10423199 | 0.87 | CA12 (0.58) | ALDH1A1TSHRL3MBTL1ATMTDP1 | |
| SCHEMBL12501820 | 0.87 | CA12 (0.58) | ALDH1A1TSHRL3MBTL1ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116870965-A | Pyridine bridge metal phthalocyanine catalyst and preparation method and application thereof | 浙江理工大学上虞工业技术研究院有限公司 | 2023-10-13 | — | — | CN | claimed |
| EP-0243652-B1 | SYNTHESIS OF HIGH PURITY 5-CHLOROISOPHTHALOYL CHLORIDE | OCCIDENTAL CHEMICAL CORPORATION (US) | 1990-10-03 | — | — | EP | claimed |
| EP-0243652-A1 | Synthesis of high purity 5-chloroisophthaloyl chloride | OCCIDENTAL CHEMICAL CORPORATION (US) | 1987-11-04 | — | — | EP | claimed |
| CN-116870965-A | Pyridine bridge metal phthalocyanine catalyst and preparation method and application thereof | 浙江理工大学上虞工业技术研究院有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-114130218-A | Polyamide reverse osmosis membrane and preparation method thereof | 山东招金膜天股份有限公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-107128038-A | Fabric composite for thermal protection article | 杜邦公司 | 2017-09-05 | — | — | CN | disclosed |
| US-9411058-B2 | Polymer composite based thermal neutron detectors | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2016-08-09 | — | — | US | disclosed |
| US-20150247938-A1 | POLYMER COMPOSITE BASED THERMAL NEUTRON DETECTORS | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2015-09-03 | — | — | US | disclosed |
| US-8796631-B2 | Polymer composite based thermal neutron detectors | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2014-08-05 | — | — | US | disclosed |
| US-20130270442-A1 | POLYMER COMPOSITE BASED THERMAL NEUTRON DETECTORS | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2013-10-17 | — | — | US | disclosed |
| CN-1562936-A | New technique for preparing oxyformyl chloride-isophthaloyl chlorine | HANGZHOU WATER TREAT TECH RES (CN) | 2005-01-12 | — | — | CN | disclosed |
| CN-1018983-B | Tetrabromobisphenol type polycarbonate film | DOW CHEMICAL CO (US) | 1992-11-11 | — | — | CN | disclosed |
| EP-0217212-B1 | SEMIPERMEABLE COMPOSITE MEMBRANE AND PROCESS FOR PREPARATION THEREOF | TORAY INDUSTRIES, INC. (JP) | 1990-11-28 | — | — | EP | disclosed |
| EP-0243652-B1 | SYNTHESIS OF HIGH PURITY 5-CHLOROISOPHTHALOYL CHLORIDE | OCCIDENTAL CHEMICAL CORPORATION (US) | 1990-10-03 | — | — | EP | disclosed |
| US-4857363-A | CROSSLINKED PIPERAZINE POLYAMIDES | TORAY INDUSTRIES, INC. (JP) | 1989-08-15 | — | — | US | disclosed |
| US-4776986-A | CATALYTIC CHLORINATION OF ISOPHTHALOYL CHLORIDE | OCCIDENTAL CHEMICAL CORPORATION (US) | 1988-10-11 | — | — | US | disclosed |
| US-4758343-A | Ultra-thin membrane of crosslinked piperazine polyamide | TORAY INDUSTRIES, INC. (JP) | 1988-07-19 | — | — | US | disclosed |
| EP-0243652-A1 | Synthesis of high purity 5-chloroisophthaloyl chloride | OCCIDENTAL CHEMICAL CORPORATION (US) | 1987-11-04 | — | — | EP | disclosed |
| EP-0217212-A2 | Semipermeable composite membrane and process for preparation thereof | TORAY INDUSTRIES, INC. (JP) | 1987-04-08 | — | — | EP | disclosed |
| US-4011203-A | FIBERS, FILMS | TOYOBO CO., LTD. (JA) | 1977-03-08 | — | — | US | disclosed |