Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 11/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31501681 | 1.00 | CYP1A2 (0.51) | CYP1A2CYP3A4KDM4ECLK4ALDH1A1 | |
| SCHEMBL25276551 | 1.00 | CYP1A2 (0.51) | CYP1A2CYP3A4KDM4ECLK4ALDH1A1 | |
| SCHEMBL31501711 | 0.89 | HTT (0.44) | CYP1A2CYP3A4KDM4ECLK4ALDH1A1 | |
| SCHEMBL25227852 | 0.89 | HTT (0.44) | CYP1A2CYP3A4KDM4ECLK4ALDH1A1 | |
| SCHEMBL31501707 | 0.88 | CYP2D6 (0.46) | CYP1A2CYP3A4KDM4ECLK4ALDH1A1 | |
| SCHEMBL25268625 | 0.88 | CYP2D6 (0.46) | CYP1A2CYP3A4KDM4ECLK4ALDH1A1 | |
| SCHEMBL31501710 | 0.85 | HTT (0.41) | CYP1A2CYP3A4KDM4ECLK4ALDH1A1 | |
| SCHEMBL25725210 | 0.85 | CYP1A2 (0.41) | CYP1A2CYP3A4KDM4ECLK4ALDH1A1 | |
| SCHEMBL25275689 | 0.84 | PDGFRB (0.43) | CYP1A2CYP3A4KDM4ECLK4ALDH1A1 | |
| SCHEMBL31501706 | 0.83 | HTT (0.43) | CYP1A2CYP3A4KDM4ECLK4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066358-A1 | Inhibitors of Menin-MLL Interaction | BALA THERAPEUTICS, INC. | 2025-02-27 | — | — | US | disclosed |
| CN-118647378-A | Inhibitors of Mei Nen protein interaction with MLL | 巴拉疗法公司 | 2024-09-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066358-A1 | Inhibitors of Menin-MLL Interaction | MLLT1, MEN1, BMI1 | CYP1A2 3937/4885CYP3A4 4263/4885KDM4E 136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.