Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 9/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25630561 | 0.89 | KIT (0.41) | CYP1A2CYP3A4ALDH1A1CLK4KDM4E | |
| SCHEMBL31027439 | 0.85 | CYP1A2 (0.51) | CYP1A2CYP3A4ALDH1A1CLK4KDM4E | |
| SCHEMBL25276551 | 0.85 | CYP1A2 (0.51) | CYP1A2CYP3A4ALDH1A1CLK4KDM4E | |
| SCHEMBL31501681 | 0.85 | CYP1A2 (0.51) | CYP1A2CYP3A4ALDH1A1CLK4KDM4E | |
| SCHEMBL25275689 | 0.84 | PDGFRB (0.43) | CYP1A2CYP3A4ALDH1A1CLK4KDM4E | |
| SCHEMBL25631166 | 0.82 | HTT (0.35) | CYP1A2CYP3A4ALDH1A1CLK4KDM4E | |
| SCHEMBL30406053 | 0.80 | KIT (0.51) | CYP1A2CYP3A4ALDH1A1CLK4MEN1 | |
| SCHEMBL25437390 | 0.80 | KIT (0.51) | CYP1A2CYP3A4ALDH1A1CLK4MEN1 | |
| SCHEMBL30405196 | 0.78 | PDGFRB (0.41) | CYP1A2CYP3A4ALDH1A1CLK4MEN1 | |
| SCHEMBL25630530 | 0.76 | PTK2 (0.50) | CYP1A2CYP3A4ALDH1A1CLK4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107696-A2 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |