Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 5/20 | 0.71 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.71 |
| ▸ | ROCK2 | O75116 | 9/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 9/20 | 0.51 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22319375 | 1.00 | PTGER4 (0.71) | PTGER4PTGER2ROCK2ROCK1LRRK2 | |
| SCHEMBL22319363 | 0.91 | PTGER4 (0.58) | PTGER4PTGER2ROCK2ROCK1LRRK2 | |
| SCHEMBL31028174 | 0.89 | PTGER4 (0.85) | PTGER4PTGER2PPARGPPARDPPARA | |
| SCHEMBL22319379 | 0.89 | PTGER4 (0.85) | PTGER4PTGER2PPARGPPARDPPARA | |
| SCHEMBL22319376 | 0.87 | PTGER4 (0.74) | PTGER4PTGER2MAPTTHRBPPARG | |
| SCHEMBL31028151 | 0.87 | PTGER4 (0.74) | PTGER4PTGER2MAPTTHRBPPARG | |
| SCHEMBL22319351 | 0.86 | PTGER4 (0.80) | PTGER4PTGER2MAPTPPARGPPARD | |
| SCHEMBL22319364 | 0.86 | PTGER4 (0.80) | PTGER4PTGER2PPARGPPARDPPARA | |
| SCHEMBL22319348 | 0.86 | PTGER4 (0.76) | PTGER4PTGER2ROCK2ROCK1PPARG | |
| SCHEMBL31028149 | 0.86 | PTGER4 (0.76) | PTGER4PTGER2ROCK2ROCK1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113646299-B | Novel N-benzyl-2-phenoxybenzamide derivatives as prostaglandin E2 (PGE 2) receptor modulators | 梅迪比奥法尔玛公司 | 2024-07-26 | — | — | CN | claimed |
| CN-113646299-B | Novel N-benzyl-2-phenoxybenzamide derivatives as prostaglandin E2 (PGE 2) receptor modulators | 梅迪比奥法尔玛公司 | 2024-07-26 | — | — | CN | disclosed |