Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 7/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 7/20 | 0.51 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 4/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 3/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31028613 | 0.93 | DDB1 (0.51) | DDB1CRBNGRM2TNKSTNKS2 | |
| SCHEMBL31028632 | 0.81 | CRBN (0.44) | DDB1CRBNTNKSTNKS2PARP1 | |
| SCHEMBL38654966 | 0.81 | DDB1 (0.54) | DDB1CRBNTNKSTNKS2PARP1 | |
| SCHEMBL31028593 | 0.80 | DDB1 (0.70) | DDB1CRBN | |
| SCHEMBL31028689 | 0.80 | HPGD (0.55) | DDB1CRBN | |
| SCHEMBL31028664 | 0.80 | DDB1 (0.42) | DDB1CRBNTNKSTNKS2PARP1 | |
| SCHEMBL31028610 | 0.78 | DDB1 (0.43) | DDB1CRBNGRM2BRD4CREBBP | |
| SCHEMBL31393572 | 0.76 | DDB1 (0.56) | DDB1CRBNGRM2TNKSTNKS2 | |
| SCHEMBL31028586 | 0.73 | CRBN (0.47) | DDB1CRBNTNKSTNKS2 | |
| SCHEMBL31028573 | 0.73 | CRBN (0.44) | DDB1CRBNTNKSTNKS2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662206-A1 | GSPT1 DEGRADER COMPOUNDS | Captor Therapeutics S.A. (PL) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024165577-A1 | GSPT1 DEGRADER COMPOUNDS | CAPTOR THERAPEUTICS S.A. (PL) | 2024-08-15 | — | — | WO | disclosed |