Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 8/20 | 0.56 |
| ▸ | CRBN | Q96SW2 | 8/20 | 0.56 |
| ▸ | AKT1 | P31749 | 2/20 | 0.49 |
| ▸ | TNKS | O95271 | 4/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | CCKBR | P32239 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38654966 | 0.81 | DDB1 (0.54) | DDB1CRBNTNKSTNKS2PARP1 | |
| SCHEMBL31028613 | 0.76 | DDB1 (0.51) | DDB1CRBNAKT1TNKSTNKS2 | |
| SCHEMBL31028596 | 0.76 | DDB1 (0.51) | DDB1CRBNAKT1TNKSTNKS2 | |
| SCHEMBL25079645 | 0.76 | DDB1 (0.61) | DDB1CRBNTNKSTNKS2PARP1 | |
| SCHEMBL31393666 | 0.75 | CRBN (0.52) | DDB1CRBNTNKSTNKS2PARP1 | |
| SCHEMBL31255355 | 0.75 | DDB1 (0.47) | DDB1CRBN | |
| SCHEMBL2573836 | 0.74 | HDAC1 (0.57) | AKT1NAMPTHDAC1GRM2 | |
| SCHEMBL31040971 | 0.72 | DDB1 (0.54) | DDB1CRBNTNKSTNKS2 | |
| SCHEMBL29691609 | 0.72 | AKT1 (0.49) | DDB1CRBNAKT1PARP1BRD4 | |
| SCHEMBL31040966 | 0.72 | DDB1 (0.65) | DDB1CRBNTNKSTNKS2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049976-A1 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | ONCOPIA THERAPEUTICS, INC. D/B/A SK LIFE SCIENCE LABS (US) | 2025-03-06 | — | — | WO | disclosed |