Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.53 |
| ▸ | CA1 | P00915 | 9/20 | 0.53 |
| ▸ | CA9 | Q16790 | 7/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 5/20 | 0.41 |
| ▸ | CA6 | P23280 | 3/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27801399 | 0.87 | CA1 (0.49) | CA2CA1CA9MAPK1FTO | |
| SCHEMBL578800 | 0.85 | CA1 (0.53) | CA2CA1CA9MAPK1FTO | |
| SCHEMBL579298 | 0.82 | CA1 (0.47) | CA2CA1CA9MAPK1FTO | |
| SCHEMBL27713085 | 0.82 | CA1 (0.44) | CA2CA1CA9MAPK1FTO | |
| SCHEMBL3717781 | 0.80 | CA2 (0.45) | CA2CA1CA9MAPK1FTO | |
| SCHEMBL578867 | 0.80 | CA2 (0.45) | CA2CA1CA9MAPK1FTO | |
| SCHEMBL3717326 | 0.80 | CA2 (0.45) | CA2CA1CA9MAPK1FTO | |
| SCHEMBL27857902 | 0.79 | CA1 (0.47) | CA2CA1CA9MAPK1FTO | |
| SCHEMBL8510750 | 0.76 | LMNA (0.42) | CA2CA1CA9MAPK1FTO | |
| SCHEMBL20502571 | 0.76 | CA1 (0.56) | CA2CA1CA9MAPK1FTO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024115549-A1 | ARYL- AND HETEROARYL-SULFONAMIDE DERIVATIVES AS CCR8 MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-06-06 | — | — | WO | claimed |
| WO-2024115549-A1 | ARYL- AND HETEROARYL-SULFONAMIDE DERIVATIVES AS CCR8 MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-06-06 | — | — | WO | disclosed |