Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 7/20 | 0.70 |
| ▸ | MAPK13 | O15264 | 6/20 | 0.70 |
| ▸ | MAPK12 | P53778 | 6/20 | 0.70 |
| ▸ | MAPK11 | Q15759 | 6/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.70 |
| ▸ | RAB9A | P51151 | 2/20 | 0.70 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.70 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.70 |
| ▸ | GMNN | O75496 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | THRB | P10828 | 1/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2125126 | 0.89 | MAPT (0.75) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL31029948 | 0.88 | MAPT (0.58) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL2127659 | 0.83 | KMT2A (0.68) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL9514606 | 0.83 | KMT2A (0.68) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL7989517 | 0.83 | MAPT (0.49) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| Pd-169316 SCHEMBL154958 | 0.82 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| Pd-169316 SCHEMBL9899161 | 0.82 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL31029952 | 0.82 | MAPT (0.57) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL67984 | 0.80 | MAPK13 (0.89) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL31029951 | 0.80 | MAPK13 (0.89) | MAPK14MAPK13MAPK12MAPK11MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118440005-A | Trisubstituted arylamine imidazole compound and preparation method and application thereof | 华中科技大学 | 2024-08-06 | — | — | CN | disclosed |